2-Propylpyrrolidine

Base Information

• Chemical Name: 2-Propylpyrrolidine
• CAS No.: 1121-44-4
• Molecular Formula: C7H15N
• Molecular Weight: 113.2007
• Hs Code.: 2933990090
• European Community (EC) Number: 837-662-2
• DSSTox Substance ID: DTXSID60396532
• Mol file: 1121-44-4.mol

Synonyms:2-propylpyrrolidine;1121-44-4;2-Propyl-pyrrolidine;Pyrrolidine, 2-propyl-;Pyrrolidine,2-propyl-;SCHEMBL551922;DTXSID60396532;MFCD02663402;STK139532;AKOS000158620;AKOS016343912;AB12028;BB 0249470;EN300-127295;N12832

Chemical Property of 2-Propylpyrrolidine

Chemical Property:

• Vapor Pressure: 3.96mmHg at 25°C
• Refractive Index: 1.428
• Boiling Point: 149.8 °C at 760 mmHg
• Flash Point: 34.5 °C
• PSA: 12.03000
• Density: 0.815 g/cm³
• LogP: 1.86730
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 113.120449483
• Heavy Atom Count: 8
• Complexity: 61.4

Purity/Quality:

97% ^*data from raw suppliers

2-Propylpyrrolidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC1CCCN1

Technology Process of 2-Propylpyrrolidine

There total 15 articles about 2-Propylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C21H27NO → 2-propylpyrrolidine (1121-44-4)

Guidance literature:

With lead(IV) tetraacetate; In toluene; at 20 ℃; for 1h; Cooling with ice;

DOI:10.1016/j.mencom.2015.11.014

Reference yield:

α-allyl-N-benzyloxycarbonylpyrrolidine (676132-43-7) → 2-propylpyrrolidine (1121-44-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 8h; under 760.051 Torr;

DOI:10.1016/j.tet.2008.02.060

Reference yield:

1-Heptylamine (111-68-2) → 2-propylpyrrolidine (1121-44-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 83 percent / triethylamine / diethyl ether / 0.5 h / Heating

2: Na₂S₂O₈, CuCl₂*2H₂O / H₂O / 5 h / 90 °C

3: 48percent HBr, phenol / H₂O / Heating

With sodium persulfate; hydrogen bromide; triethylamine; phenol; In diethyl ether; water;

DOI:10.1016/S0040-4020(01)97199-6

upstream raw materials:

2-n-propylpyrrole

1-(methylsulfonyl)-2-propylpyrrolidine

3-(furan-2-yl)propan-1-amine

water

Downstream raw materials:

1-benzenesulfonyl-2-propyl-pyrrolidine

2-Propyl-N-(phenylcarbamoyl)pyrrolidine

N-[4-(2-Propyl-pyrrolidine-1-sulfonyl)-phenyl]-acetamide; hydrochloride

2-propyl-1-tosylpyrrolidine