3-(2-furyl)propan-1-amine oxalate

Base Information

• Chemical Name: 3-(2-furyl)propan-1-amine oxalate
• CAS No.: 4428-38-0
• Molecular Formula: C7H11NO
• Molecular Weight: 125.16800
• Mol file: 4428-38-0.mol

Synonyms:2-<3-Amino-propyl>-furan;3-furan-2-yl-propylamine;3-furan-2-yl-isoquinolin-1-ylamine;

Chemical Property of 3-(2-furyl)propan-1-amine oxalate

Chemical Property:

• Vapor Pressure: 0.718mmHg at 25°C
• Boiling Point: 184.9oC at 760 mmHg
• PKA: 10.13±0.10(Predicted)
• Flash Point: 65.6oC
• PSA: 39.16000
• Density: 0.999g/cm3
• LogP: 1.87120

Purity/Quality:

98%min ^*data from raw suppliers

3-(2-furyl)propan-1-amine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(2-furyl)propan-1-amine oxalate

There total 7 articles about 3-(2-furyl)propan-1-amine oxalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-(3-azidopropyl)furan (684221-23-6) → 3-(furan-2-yl)propan-1-amine (4428-38-0)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol; at 25 ℃; for 8h;

Reference yield: 92.0%

3-(furan-2-yl)propanenitrile (21446-61-7) → 3-(furan-2-yl)propan-1-amine (4428-38-0)

Guidance literature:

3-(furan-2-yl)propanenitrile; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 1h; Inert atmosphere;

With water; sodium hydroxide; In tetrahydrofuran; at -10 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2011.11.055

Reference yield:

(E)-3-(2-furanyl)-2-propenal (39511-08-5) → 3-(furan-2-yl)propan-1-amine (4428-38-0)

Guidance literature:

With ethanol; ammonia; nickel; at 70 - 100 ℃; under 73550.8 Torr; Hydrogenation;

upstream raw materials:

3-(furan-2-yl)propanenitrile

(E)-3-(2-furanyl)-2-propenal

ethanol

ammonia

Downstream raw materials:

2-[(2-ethylsulfanylacetyl)-(3-furan-2-yl-propyl)amino]-cyclohex-1-ene-carboxylic acid ethyl ester

2-propylpyrrolidine

3-tetrahydrofuran-2-yl-propylamine

1-(3-Furan-2-yl-propyl)-3-phenyl-urea

Refernces

• 1、 Shengule, Sudhir R.,Willis, Anthony,Pyne, Stephen G.. "Synthesis of spirocyclic azacycles from the cyclization of furan tethered N-acyliminium ions". experimental part. p. 1207 - 1215. Retrieved 2012/02/16.