5-methyl-6-benzyl-5H-dibenzazepinium bromide

Base Information

• Chemical Name: 5-methyl-6-benzyl-5H-dibenzazepinium bromide
• CAS No.: 106569-21-5
• Molecular Formula: Br*C₂₂H₂₀N
• Molecular Weight: 378.311
• Mol file: 106569-21-5.mol

Synonyms:

Chemical Property of 5-methyl-6-benzyl-5H-dibenzazepinium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-methyl-6-benzyl-5H-dibenzazepinium bromide

There total 4 articles about 5-methyl-6-benzyl-5H-dibenzazepinium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2'-(1-bromoethyl)<1,1'-biphenyl>-2-carboxaldehyde (106569-06-6) + benzylamine (100-46-9) → 5-methyl-6-benzyl-5H-dibenzazepinium bromide (106569-21-5)

Guidance literature:

In benzene; for 20h; Heating;

DOI:10.1021/jo00380a010

Reference yield:

2-<2'-formyl-<1,1'-biphenyl>-2-yl>-1,3-dioxolane (57741-33-0) → 5-methyl-6-benzyl-5H-dibenzazepinium bromide (106569-21-5)

Guidance literature:

Multi-step reaction with 3 steps

1: diethyl ether; tetrahydrofuran / 16 h / Heating

2: 75 percent / concd. aq. HBr / CH₂Cl₂ / 16 h / Heating

3: 88 percent / benzene / 20 h / Heating

With hydrogen bromide; In tetrahydrofuran; diethyl ether; dichloromethane; benzene;

DOI:10.1021/jo00380a010

Reference yield:

1-<2'-(<1,3-dioxolan>-2-yl)-<1,1'-biphenyl>-2-yl>ethanol (106569-04-4) → 5-methyl-6-benzyl-5H-dibenzazepinium bromide (106569-21-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / concd. aq. HBr / CH₂Cl₂ / 16 h / Heating

2: 88 percent / benzene / 20 h / Heating

With hydrogen bromide; In dichloromethane; benzene;

DOI:10.1021/jo00380a010

upstream raw materials:

2'-(1-bromoethyl)<1,1'-biphenyl>-2-carboxaldehyde

benzylamine

2-<2'-formyl-<1,1'-biphenyl>-2-yl>-1,3-dioxolane

1-<2'-(<1,3-dioxolan>-2-yl)-<1,1'-biphenyl>-2-yl>ethanol