57741-33-0Relevant articles and documents
Synthesis of Diverse 6-Oxa-allocolchicinoids by a Suzuki-Miyaura Coupling, Acid-Catalyzed Intramolecular Transacetalization Strategy
Yadav, Dharmendra B.,Taleli, Lebusetsa,Van Der Westhuyzen, Alet E.,Fernandes, Manuel A.,Dragoun, Maxim,Prokop, Aram,Schmalz, Hans-Günther,De Koning, Charles B.,Van Otterlo, Willem A. L.
, p. 5167 - 5182 (2015)
The synthesis of allocolchicine analogues is of importance as these compounds have been found to possess promising anticancer activity by affecting tubulin polymerization. In this paper, the synthesis of 28 novel substituted 6-oxa-allocolchicinoids is rep