2-(3-Aminophenylamino)acetic acid

Base Information

• Chemical Name: 2-(3-Aminophenylamino)acetic acid
• CAS No.: 6262-30-2
• Molecular Formula: C8H10N2O2
• Molecular Weight: 166.1772
• DSSTox Substance ID: DTXSID40593446
• Wikidata: Q82487936
• Mol file: 6262-30-2.mol

Synonyms:6262-30-2;2-(3-AMINOPHENYLAMINO)ACETIC ACID;2-(3-aminoanilino)acetic acid;N-(3-Aminophenyl)glycine;SCHEMBL6370197;DTXSID40593446;2-((3-Aminophenyl)amino)acetic acid;AKOS011538592

Chemical Property of 2-(3-Aminophenylamino)acetic acid

Chemical Property:

• Boiling Point: 460 °C at 760 mmHg
• Flash Point: 232 °C
• PSA: 75.35000
• Density: 1.358 g/cm³
• LogP: 1.41950
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 166.074227566
• Heavy Atom Count: 12
• Complexity: 161

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC(=C1)NCC(=O)O)N

Technology Process of 2-(3-Aminophenylamino)acetic acid

There total 1 articles about 2-(3-Aminophenylamino)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R/S)-(3-nitrophenyl)glycine (10242-06-5) → 2-((3-aminophenyl)amino)acetic acid (6262-30-2)

Guidance literature:

With ammonia; iron(II) sulfate;

Reference yield:

2-methoxy-4-(β-sulfatoethylsulfonyl)-1-aminobenzene (26672-22-0) + 2-((3-aminophenyl)amino)acetic acid (6262-30-2) → C17H18N4O9S2(2-)*2Na(1+)

Guidance literature:

2-methoxy-4-(β-sulfatoethylsulfonyl)-1-aminobenzene; With hydrogenchloride; sodium nitrite; In water; at 0 - 5 ℃; for 2h;

2-((3-aminophenyl)amino)acetic acid; With sodium carbonate; In water; at 5 - 15 ℃; for 2h; pH=3 - 3.5;

Reference yield:

2-(p-aminophenylsulfonyl)ethyl hydrogen sulfate (2494-89-5) + 2-((3-aminophenyl)amino)acetic acid (6262-30-2) → C17H19N4O11S3(1-)*Na(1+)

Guidance literature:

2-(p-aminophenylsulfonyl)ethyl hydrogen sulfate; With hydrogenchloride; sodium nitrite; In water; at 0 - 5 ℃; for 2h;

2-((3-aminophenyl)amino)acetic acid; With sodium carbonate; In water; at 5 - 15 ℃; for 2h; pH=3 - 3.5;

upstream raw materials:

(R/S)-(3-nitrophenyl)glycine