2-Hydroxy-4-phenylnicotinic acid

Base Information

Chemical Name:2-Hydroxy-4-phenylnicotinic acid
CAS No.:133609-29-7
Molecular Formula:C₁₂H₉NO₃
Molecular Weight:215.208
Hs Code.:
DSSTox Substance ID:DTXSID001219458

Synonyms:133609-29-7;2-Hydroxy-4-phenylnicotinic acid;SCHEMBL4428264;DTXSID001219458;MFCD16309035;AKOS022305445;2-oxo-4-phenyl-1H-pyridine-3-carboxylic acid;1,2-Dihydro-2-oxo-4-phenyl-3-pyridinecarboxylic acid

Suppliers and Price of 2-Hydroxy-4-phenylnicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-Hydroxy-4-phenylnicotinic acid

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:215.058243149
Heavy Atom Count:16
Complexity:376

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(C(=O)NC=C2)C(=O)O

Technology Process of 2-Hydroxy-4-phenylnicotinic acid

There total 3 articles about 2-Hydroxy-4-phenylnicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 14045-37-5
1,2-dihydro-2-oxo-4-phenylpyridine-3-carbonitrile

: 133609-29-7
2-oxo-4-phenyl-1,2-dihydropyridine-3-carboxylic acid

Guidance literature:: With sulfuric acid; sodium nitrite; Yield given. Multistep reaction; 1.) 90 deg C, 2 h, 2.) 90 deg C;

Reference yield:

: 162738-55-8
2-cyano-3-phenylbutyramide

: 133609-29-7
2-oxo-4-phenyl-1,2-dihydropyridine-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 6 h / Heating

2: sodium hydroxide / 140 °C

With sodium hydroxide; In N,N-dimethyl-formamide;
DOI:10.1021/jm00046a015

Reference yield:

: 124571-67-1
2-(3-dimethylamino-1-phenyl-2-propenylidene)-1,3-propanedinitrile

: 133609-29-7
2-oxo-4-phenyl-1,2-dihydropyridine-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / H₂SO₄, H₂O / acetic acid / 2 h / Heating

2: 1.) 75percent aq. H₂SO₄, 1.) sodium nitrite / 1.) 90 deg C, 2 h, 2.) 90 deg C

With sulfuric acid; water; sodium nitrite; In acetic acid;