2H-1-Benzopyran-2-one, 7,8-bis(acetyloxy)-4-phenyl-

Base Information

• Chemical Name: 2H-1-Benzopyran-2-one, 7,8-bis(acetyloxy)-4-phenyl-
• CAS No.: 24258-37-5
• Molecular Formula: C₁₉H₁₄O₆
• Molecular Weight: 338.317
• DSSTox Substance ID: DTXSID501230946
• Mol file: 24258-37-5.mol

Synonyms:24258-37-5;2H-1-Benzopyran-2-one, 7,8-bis(acetyloxy)-4-phenyl-;Oprea1_787018;7,8-diacetoxy-4-phenylcoumarin;DTXSID501230946;STK713356;AKOS005531673;2-oxo-4-phenyl-2H-chromene-7,8-diyl diacetate;7,8-Bis(acetyloxy)-4-phenyl-2H-1-benzopyran-2-one

Chemical Property of 2H-1-Benzopyran-2-one, 7,8-bis(acetyloxy)-4-phenyl-

Chemical Property:

• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 338.07903816
• Heavy Atom Count: 25
• Complexity: 575

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)OC1=C(C2=C(C=C1)C(=CC(=O)O2)C3=CC=CC=C3)OC(=O)C

Technology Process of 2H-1-Benzopyran-2-one, 7,8-bis(acetyloxy)-4-phenyl-

There total 10 articles about 2H-1-Benzopyran-2-one, 7,8-bis(acetyloxy)-4-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 3-oxo-3-phenylpropionate (94-02-0) → 7,8-diacetoxy-4-phenylcoumarin (24258-37-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / ZrCl₄ / 0.17 h / 20 °C

2: pyridine

With pyridine; zirconium(IV) chloride;

DOI:10.1016/j.tetlet.2005.06.166

Reference yield:

2-hydroxyresorcinol (87-66-1) → 7,8-diacetoxy-4-phenylcoumarin (24258-37-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / ZrCl₄ / 0.17 h / 20 °C

2: pyridine

With pyridine; zirconium(IV) chloride;

DOI:10.1016/j.tetlet.2005.06.166

Reference yield:

ethyl 3-oxo-3-phenylpropionate (94-02-0) → 7,8-diacetoxy-4-phenylcoumarin (24258-37-5)

Guidance literature:

Multi-step reaction with 2 steps

1: H₃PO₄

2: pyridine; 4-(N,N-dimethylamino)pyridine

With pyridine; dmap; phosphoric acid; 1: Pechmann condensation;

DOI:10.1016/j.bmc.2005.04.023

upstream raw materials:

2,3,4-trihydroxybenzophenone

sodium acetate

acetic anhydride

7,8-dihydroxy-4-phenyl-2H-chromen-2-one

Downstream raw materials:

7,8-dihydroxy-4-phenyl-2H-chromen-2-one