1-trityl-3,5-dimethyl-1H-pyrazol-4-ylboronate pinacol ester

Base Information

Chemical Name:1-trityl-3,5-dimethyl-1H-pyrazol-4-ylboronate pinacol ester
CAS No.:1874148-66-9
Molecular Formula:C₃₀H₃₃BN₂O₂
Molecular Weight:464.415
Hs Code.:

Synonyms:

Suppliers and Price of 1-trityl-3,5-dimethyl-1H-pyrazol-4-ylboronate pinacol ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
3,5-Dimethyl-1-trityl-1H-pyrazole-4-boronicAcidPinacolEster
5g
$ 863.00

AK Scientific
3,5-Dimethyl-1-trityl-1H-pyrazole-4-boronicAcidPinacolEster
250mg
$ 262.00

Total 2 raw suppliers

Chemical Property of 1-trityl-3,5-dimethyl-1H-pyrazol-4-ylboronate pinacol ester

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

3,5-Dimethyl-1-trityl-1H-pyrazole-4-boronicAcidPinacolEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-trityl-3,5-dimethyl-1H-pyrazol-4-ylboronate pinacol ester

There total 4 articles about 1-trityl-3,5-dimethyl-1H-pyrazol-4-ylboronate pinacol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 919802-98-5
4-bromo-3,5-dimethyl-1-trityl-1H-pyrazole

: 76-09-5
2,3-dimethyl-2,3-butane diol

: 5419-55-6
Triisopropyl borate

: 1874148-66-9
1-trityl-3,5-dimethyl-1H-pyrazol-4-ylboronate pinacol ester

Guidance literature:: 4-bromo-3,5-dimethyl-1-trityl-1H-pyrazole; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

Triisopropyl borate; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 2h; Inert atmosphere;

2,3-dimethyl-2,3-butane diol; With acetic acid; In tetrahydrofuran; hexane; for 1h; Inert atmosphere;
DOI:10.1016/j.tetlet.2016.01.043

Reference yield: 92.0%

: 857530-80-4
3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

: 76-83-5
trityl chloride

: 1874148-66-9
1-trityl-3,5-dimethyl-1H-pyrazol-4-ylboronate pinacol ester

Guidance literature:: 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; With trialkylamine; In chloroform; at 50 ℃; for 0.5h;

trityl chloride; In chloroform; at 50 ℃; for 6h;
DOI:10.1021/acs.inorgchem.1c03049

Reference yield:

: 76-83-5
trityl chloride

: 1874148-66-9
1-trityl-3,5-dimethyl-1H-pyrazol-4-ylboronate pinacol ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0 - 20 °C / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere

2.2: 2 h / -78 - 20 °C / Inert atmosphere

2.3: 1 h / Inert atmosphere

With n-butyllithium; sodium hydride; In tetrahydrofuran; hexane; mineral oil;
DOI:10.1016/j.tetlet.2016.01.043