Technology Process of 3a,4,7,7a-tetrahydro-2-phenyl-4-pentamethyldisilylisoindol-1,3(2H)-dione
There total 6 articles about 3a,4,7,7a-tetrahydro-2-phenyl-4-pentamethyldisilylisoindol-1,3(2H)-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 36 percent / tetrahydrofuran / 4 h / Heating
2: 85 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating
3: 74 percent / manganese dioxide / light petroleum / 8 h / Ambient temperature
4: 1.) magnesium / 1.) ether, reflux, 1 h, 2.) reflux, 4 h
5: 73 percent / toluene-p-sulphonic acid / diethyl ether / 0.5 h / Ambient temperature
6: 1.) toluene-p-sulphonic acid, 2.) hydroquinone / 1.) ether, room temperature, 1 h, 2.) benzene, 60 deg C, 24 h
With
manganese(IV) oxide; lithium aluminium tetrahydride; toluene-4-sulfonic acid; magnesium; hydroquinone;
In
tetrahydrofuran; diethyl ether; Petroleum ether;
DOI:10.1039/P19810002415
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) magnesium / 1.) ether, reflux, 1 h, 2.) reflux, 4 h
2: 73 percent / toluene-p-sulphonic acid / diethyl ether / 0.5 h / Ambient temperature
3: 1.) toluene-p-sulphonic acid, 2.) hydroquinone / 1.) ether, room temperature, 1 h, 2.) benzene, 60 deg C, 24 h
With
toluene-4-sulfonic acid; magnesium; hydroquinone;
In
diethyl ether;
DOI:10.1039/P19810002415
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 74 percent / manganese dioxide / light petroleum / 8 h / Ambient temperature
2: 1.) magnesium / 1.) ether, reflux, 1 h, 2.) reflux, 4 h
3: 73 percent / toluene-p-sulphonic acid / diethyl ether / 0.5 h / Ambient temperature
4: 1.) toluene-p-sulphonic acid, 2.) hydroquinone / 1.) ether, room temperature, 1 h, 2.) benzene, 60 deg C, 24 h
With
manganese(IV) oxide; toluene-4-sulfonic acid; magnesium; hydroquinone;
In
diethyl ether; Petroleum ether;
DOI:10.1039/P19810002415
