1,2-Bis-(phenylsulfonyl)-perfluorethan

Base Information

• Chemical Name: 1,2-Bis-(phenylsulfonyl)-perfluorethan
• CAS No.: 27605-42-1
• Molecular Formula: C₁₄H₁₀F₄O₄S₂
• Molecular Weight: 382.357
• Mol file: 27605-42-1.mol

Synonyms:

Chemical Property of 1,2-Bis-(phenylsulfonyl)-perfluorethan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-Bis-(phenylsulfonyl)-perfluorethan

There total 8 articles about 1,2-Bis-(phenylsulfonyl)-perfluorethan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

difluoromethyl phenyl sulfone (1535-65-5) + 2-isocyanobiphenyl (3128-77-6) → 1,2-Bis-(phenylsulfonyl)-perfluorethan (27605-42-1) + 6-(difluoro(phenylsulfonyl)methyl)phenanthridine

Guidance literature:

With [bis(acetoxy)iodo]benzene; sodium t-butanolate; In N,N-dimethyl-formamide; at -60 ℃; for 1h; Temperature; Reagent/catalyst; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.6b03013

Reference yield:

difluoromethyl phenyl sulfone (1535-65-5) + 2-isocyanobiphenyl (3128-77-6) → 1,2-Bis-(phenylsulfonyl)-perfluorethan (27605-42-1) + 6-(difluoro(phenylsulfonyl)methyl)phenanthridine + difluorodi(phenanthridin-6-yl)methane

Guidance literature:

With [bis(acetoxy)iodo]benzene; sodium t-butanolate; In N,N-dimethyl-formamide; at -10 ℃; for 1h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.6b03013

Reference yield:

difluoromethyl phenyl sulfide (1535-67-7) → 1,2-Bis-(phenylsulfonyl)-perfluorethan (27605-42-1)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium periodate; rhodium(III) chloride hydrate / 1,2-dimethoxyethane; water; acetonitrile; tetrachloromethane / 5 h / 20 °C

2: [bis(acetoxy)iodo]benzene; sodium t-butanolate / N,N-dimethyl-formamide / 1 h / -60 °C / Schlenk technique; Inert atmosphere

With sodium periodate; [bis(acetoxy)iodo]benzene; rhodium(III) chloride hydrate; sodium t-butanolate; In tetrachloromethane; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1021/acs.orglett.6b03013

upstream raw materials:

thiophenol

difluoromethyl phenyl sulfide

difluoromethyl phenyl sulfone

2-isocyanobiphenyl