2-bromo-3-phenylpropionyl chloride

Base Information

Chemical Name:2-bromo-3-phenylpropionyl chloride
CAS No.:81136-07-4
Molecular Formula:C₉H₈BrClO
Molecular Weight:247.519
Hs Code.:

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Suppliers and Price of 2-bromo-3-phenylpropionyl chloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-bromo-3-phenylpropionyl chloride

Chemical Property:

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Technology Process of 2-bromo-3-phenylpropionyl chloride

There total 11 articles about 2-bromo-3-phenylpropionyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 16503-53-0
2-bromo-3-phenylpropanoic acid

: 81136-07-4,42762-86-7
2-bromo-3-phenylpropionyl chloride

Guidance literature:: With phosphorus pentachloride; inactive α-bromo-β-phenyl-propionyl chloride;

Reference yield:

: 645-45-4
hydrocinnamic acid chloride

: 81136-07-4,42762-86-7
2-bromo-3-phenylpropionyl chloride

Guidance literature:: With bromine; at 65 - 70 ℃;
DOI:10.1021/ja01271a039

Reference yield:

: 150-30-1,25191-15-5,658-69-5,67675-33-6
Phenylalanine

: 81136-07-4,42762-86-7
2-bromo-3-phenylpropionyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: sodium nitrite; hydrogen bromide; potassium bromide / -13 °C

2: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 20 °C

With thionyl chloride; hydrogen bromide; N,N-dimethyl-formamide; potassium bromide; sodium nitrite; In dichloromethane;
DOI:10.1080/00397911.2011.608142