ETHYL-2-AMINO-4,5-DIETHOXYBENZOATE

Base Information

• Chemical Name: ETHYL-2-AMINO-4,5-DIETHOXYBENZOATE
• CAS No.: 460750-27-0
• Molecular Formula: C13H19 N O4
• Molecular Weight: 253.298
• Hs Code.: 2922509090
• Mol file: 460750-27-0.mol

Synonyms:2-Amino-4,5-diethoxybenzoicacid ethyl ester; Ethyl 2-amino-4,5-diethoxybenzoate

Chemical Property of ETHYL-2-AMINO-4,5-DIETHOXYBENZOATE

Chemical Property:

• PSA: 70.78000
• LogP: 2.82410

Purity/Quality:

99% ^*data from raw suppliers

ETHYL-2-AMINO-4,5-DIETHOXYBENZOATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL-2-AMINO-4,5-DIETHOXYBENZOATE

There total 3 articles about ETHYL-2-AMINO-4,5-DIETHOXYBENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4,5-diethoxy-2-nitrobenzoic acid ethyl ester (460750-26-9) → 2-amino-4,5-diethoxybenzoic acid ethyl ester (460750-27-0)

Guidance literature:

With hydrogen; 10percent Pd/C; In ethanol; at 25 ℃; under 2585.81 Torr;

DOI:10.1021/jm010496a

Reference yield: 99.0%

→ 2-amino-4,5-diethoxybenzoic acid ethyl ester (460750-27-0)

Guidance literature:

Reference yield:

3,4-diethoxybenzoic acid ethyl ester (75332-44-4) → 2-amino-4,5-diethoxybenzoic acid ethyl ester (460750-27-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / glacial AcOH; conc. HNO₃ / 3 h

2: 100 percent / H₂ / 10percent Pd/C / ethanol / 25 °C / 2585.81 Torr

With hydrogen; nitric acid; acetic acid; 10percent Pd/C; In ethanol;

DOI:10.1021/jm010496a

upstream raw materials:

4,5-diethoxy-2-nitrobenzoic acid ethyl ester

3,4-diethoxybenzoic acid ethyl ester

Downstream raw materials:

6,7-diethoxy-3H-quinazolin-4-one

(2-chloromethyl-6,7-diethoxy-quinazolin-4-yl)-[3-(2-methyl-thiazol-4-yl)-phenyl]-amine

2-bromo-1-[3-(6,7-diethoxy-quinazolin-4-ylamino)-phenyl]-ethanone

1-[3-(6,7-diethoxy-quinazolin-4-ylamino)-phenyl]-ethanone