4-BENZYLOXY-2-METHYLBENZOIC ACID

Base Information

• Chemical Name: 4-BENZYLOXY-2-METHYLBENZOIC ACID
• CAS No.: 17819-91-9
• Molecular Formula: C15H14 O3
• Molecular Weight: 242.274
• Hs Code.: 2918990090
• Mol file: 17819-91-9.mol

Synonyms:Benzoic-carboxy-14Cacid, 2-methyl-4-(phenylmethoxy)- (9CI); o-Toluic-carboxy-14C acid,4-(benzyloxy)- (8CI); 4-Benzyloxy-2-methylbenzoic acid;4-Carboxy-14C-3-methylphenyl benzyl ether

Chemical Property of 4-BENZYLOXY-2-METHYLBENZOIC ACID

Chemical Property:

• PSA: 46.53000
• LogP: 3.27220
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

4-Benzyloxy-2-methylbenzoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BENZYLOXY-2-METHYLBENZOIC ACID

There total 2 articles about 4-BENZYLOXY-2-METHYLBENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(benzyloxy)-1-bromo-2-methylbenzene (17671-75-9) → 4-benzyloxy-2-methylbenzoic acid (17819-91-9)

Guidance literature:

With carbon dioxide; iodine; In tetrahydrofuran;

Reference yield:

4-benzyloxy-2-methyl-benzaldehyde (101093-56-5) → 4-benzyloxy-2-methylbenzoic acid (17819-91-9)

Guidance literature:

4-benzyloxy-2-methyl-benzaldehyde; With sodium chlorite; sodium dihydrogenphosphate; aminosulfonic acid; In 1,4-dioxane; water; at 10 ℃; for 0.333333h;

With sodium sulfite; In 1,4-dioxane; water; at 10 ℃; for 0.25h;

With hydrogenchloride; In 1,4-dioxane; water;

Reference yield: 72.0%

3-Amino-1,2-propanediol (616-30-8,13552-31-3,98923-21-8) + 4-benzyloxy-2-methylbenzoic acid (17819-91-9) → C18H21NO4

Guidance literature:

With 1-hydroxy-pyrrolidine-2,5-dione; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

upstream raw materials:

4-(benzyloxy)-1-bromo-2-methylbenzene

4-benzyloxy-2-methyl-benzaldehyde

Downstream raw materials:

methyl 4-benzyloxy-2-methylbenzoate

4-benzyloxy-2-methylphenylmethanol

4-benzyloxy-2-methyl-benzaldehyde

Refernces

• 1、 -. "INDOLOYLGUANIDINE DERIVATIVES". . . Retrieved 2008/06/13.