tert-butyl octahydro-4-hydroxyindole-1-carboxylate

Base Information

Chemical Name:tert-butyl octahydro-4-hydroxyindole-1-carboxylate
CAS No.:543910-49-2
Molecular Formula:C₁₃H₂₃NO₃
Molecular Weight:241.331
Hs Code.:2933990090
Mol file:543910-49-2.mol

Synonyms:tert-Butyl 4-hydroxyoctahydro-1H-indole-1-carboxylate;tert-Butyl octahydro-4-hydroxyindole-1-carboxylate;

Suppliers and Price of tert-butyl octahydro-4-hydroxyindole-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl4-hydroxyoctahydro-1H-indole-1-carboxylate 95+%
1g
$ 772.00

ChemScene
1H-Indole-1-carboxylicacid,octahydro-4-hydroxy-,1,1-dimethylethylester,(3aR,4S,7aR)-
1g
$ 750.00

Chemenu
tert-butyl4-hydroxyoctahydro-1H-indole-1-carboxylate 95%
1g
$ 729.00

Total 8 raw suppliers

Chemical Property of tert-butyl octahydro-4-hydroxyindole-1-carboxylate

Chemical Property:

Vapor Pressure:4.01E-06mmHg at 25°C
Boiling Point:345oC at 760 mmHg
Flash Point:162.5oC
PSA：49.77000
Density:1.117g/cm3
LogP:2.09470

Purity/Quality:

99% ^*data from raw suppliers

tert-Butyl4-hydroxyoctahydro-1H-indole-1-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl octahydro-4-hydroxyindole-1-carboxylate

There total 7 articles about tert-butyl octahydro-4-hydroxyindole-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 877170-76-8
4-oxo-4,5,6,7-tetrahydro-indole-1-carboxylic acid tert-butyl ester

: 1821237-04-0,543910-49-2
tert-butyl 4-hydroxyoctahydro-1H-indole-1-carboxylate

Guidance literature:: With platinum(IV) oxide; hydrogen; acetic acid; In methanol; at 50 ℃; for 3h; under 7500.75 Torr;

Reference yield: 67.0%

: 877170-76-8
4-oxo-4,5,6,7-tetrahydro-indole-1-carboxylic acid tert-butyl ester

: 1821237-04-0,543910-49-2
(3aRS,4SR,7aRS)-4-hydroxy-octahydro-indole-1-carboxylic acid tert-butyl ester

Guidance literature:: With platinum on carbon; hydrogen; In methanol; at 20 ℃; for 92h; under 750.075 Torr;
DOI:10.1016/j.bmc.2014.09.033

Reference yield:

: 13754-86-4
1,5,6,7-tetrahydro-indol-4-one

: 1821237-04-0,543910-49-2
(3aRS,4SR,7aRS)-4-hydroxy-octahydro-indole-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / tetrahydrofuran / 2 h / Reflux

2: hydrogen; platinum on carbon / methanol / 92 h / 20 °C / 750.08 Torr

With platinum on carbon; potassium tert-butylate; hydrogen; In tetrahydrofuran; methanol;
DOI:10.1016/j.bmc.2014.09.033