1-(6-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine

Base Information

Chemical Name:1-(6-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine
CAS No.:132834-56-1
Molecular Formula:C10H11 Cl F3 N3
Molecular Weight:265.66300
Hs Code.:2933990090
UNII:TUK9RFW5YL
DSSTox Substance ID:DTXSID70430870
Nikkaji Number:J1.179.241C
Wikipedia:ORG-12962
Wikidata:Q7101734
Pharos Ligand ID:N5KW5X93DBX5
ChEMBL ID:CHEMBL506999
Mol file:132834-56-1.mol

Synonyms:132834-56-1;1-(6-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine;ORG-12962;org 12962;1-[6-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazine;1-[6-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazine;piperazine, 1-[6-chloro-5-(trifluoromethyl)-2-pyridinyl]-;Org12962;1-[6-Chloro-5-(trifluoromethyl)-2-pyridinyl]-piperazine;TUK9RFW5YL;D0N7HY;GTPL170;SCHEMBL906077;[6-chloro-5-(trifluoromethyl)-2-pyridyl]piperazine;CHEMBL506999;BDBM85533;DTXSID70430870;Org 12,962;ORG12692;MFCD00892750;AKOS005073183;KD-0713;NCGC00370871-01;HY-118152;LS-193739;A2811;AM20050771;CS-0065306;FT-0703406;C72316;L003895;J-503456;Q7101734;2-Chloro-3-(trifluoromethyl)-6-(1-piperazinyl)pyridine;Piperazine,1-[6-chloro-5-(trifluoromethyl)-2-pyridinyl]-

Suppliers and Price of 1-(6-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-[6-Chloro-5-(trifluoromethyl)-2-pyridinyl]-piperazine >95%
1g
$ 454.00

Matrix Scientific
1-[6-Chloro-5-(trifluoromethyl)-2-pyridinyl]-piperazine >95%
500mg
$ 362.00

CSNpharm
Org-12962
100mg
$ 45.00

Crysdot
1-(6-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine 95+%
1g
$ 317.00

ChemScene
Org-12962 >98.0%
5mg
$ 50.00

ChemScene
Org-12962 >98.0%
10mg
$ 85.00

Chemenu
1-(6-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine 95%
1g
$ 299.00

Apolloscientific
1-[6-Chloro-5-(trifluoromethyl)-2-pyridinyl]piperazine
500mg
$ 270.00

Apolloscientific
1-[6-Chloro-5-(trifluoromethyl)-2-pyridinyl]piperazine
1g
$ 250.00

Ambeed
1-(6-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine 95%
250mg
$ 76.00

Total 24 raw suppliers

Chemical Property of 1-(6-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Melting Point:76～78℃
Boiling Point:286.004oC at 760 mmHg
PKA:8.38±0.10(Predicted)
Flash Point:126.771oC
PSA：28.16000
Density:1.454g/cm3
LogP:2.55720
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:265.0593595
Heavy Atom Count:17
Complexity:256

Purity/Quality:

97% ^*data from raw suppliers

1-[6-Chloro-5-(trifluoromethyl)-2-pyridinyl]-piperazine >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)C2=NC(=C(C=C2)C(F)(F)F)Cl

Technology Process of 1-(6-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine

There total 2 articles about 1-(6-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 132834-56-1
1-[6-chloro-5-(trifluoromethyl)-2-pyridinyl]-piperazine

Guidance literature:

Reference yield:

: 110-85-0
piperazine

: 55304-75-1
2,6-dichloro-3-(trifluoromethyl)pyridine

: 132834-56-1
1-[6-chloro-5-(trifluoromethyl)-2-pyridinyl]-piperazine

Guidance literature:: In ethanol; ethyl acetate;

Reference yield:

: 122-99-6,56257-90-0,9004-78-8
2-Phenoxyethanol

: 64-19-7,77671-22-8
acetic acid

: 132834-56-1
1-[6-chloro-5-(trifluoromethyl)-2-pyridinyl]-piperazine

: 1-[6-(2-phenoxy-ethoxy)-5-trifluoromethyl-pyridin-2-yl]-piperazine, acetate

Guidance literature:: 2-Phenoxyethanol; 1-[6-chloro-5-(trifluoromethyl)-2-pyridinyl]-piperazine; With potassium 2,2-dimethyl-1-propanolate; In dimethyl sulfoxide; at 20 ℃; for 2h;

acetic acid;