C₃₅H₄₅N₅O₉

Base Information

• Chemical Name: C₃₅H₄₅N₅O₉
• CAS No.: 1053716-70-3
• Molecular Formula: C₃₅H₄₅N₅O₉
• Molecular Weight: 679.77
• Mol file: 1053716-70-3.mol

Synonyms:

Chemical Property of C₃₅H₄₅N₅O₉

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₅H₄₅N₅O₉

There total 8 articles about C₃₅H₄₅N₅O₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-acetamido-4-amino-2,6-anhydro-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic acid (130525-62-1) → C35H45N5O9 (1053716-70-3)

Guidance literature:

Multi-step reaction with 8 steps

1: aq. NaHCO₃ / dioxane / 18 h / 23 °C

2: aq. HCl / CH₂Cl₂ / 24 h / 23 °C

3: aq. NaIO₄ / methanol / 3 h / 23 °C

4: NaClO₂, aq. KH₂PO₄, cyclohexene / 2-methyl-propan-2-ol / 18 h / 23 °C

5: 97 percent / pyridine / dimethylformamide / 3 h / 23 °C

6: tetrahydrofuran / 4 h / 23 °C

7: HCl / dioxane / 0.5 h

8: tetrahydrofuran; dimethylformamide / 18 h / 23 °C

With pyridine; hydrogenchloride; sodium chlorite; sodium periodate; potassium dihydrogenphosphate; sodium hydrogencarbonate; cyclohexene; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; N,N-dimethyl-formamide; tert-butyl alcohol;

Reference yield:

(4S,5R,6R)-5-Acetylamino-4-tert-butoxycarbonylamino-6-((1R,2R)-1,2,3-trihydroxy-propyl)-5,6-dihydro-4H-pyran-2-carboxylic acid (166830-74-6) → C35H45N5O9 (1053716-70-3)

Guidance literature:

Multi-step reaction with 7 steps

1: aq. HCl / CH₂Cl₂ / 24 h / 23 °C

2: aq. NaIO₄ / methanol / 3 h / 23 °C

3: NaClO₂, aq. KH₂PO₄, cyclohexene / 2-methyl-propan-2-ol / 18 h / 23 °C

4: 97 percent / pyridine / dimethylformamide / 3 h / 23 °C

5: tetrahydrofuran / 4 h / 23 °C

6: HCl / dioxane / 0.5 h

7: tetrahydrofuran; dimethylformamide / 18 h / 23 °C

With pyridine; hydrogenchloride; sodium chlorite; sodium periodate; potassium dihydrogenphosphate; cyclohexene; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; N,N-dimethyl-formamide; tert-butyl alcohol;

Reference yield:

(4S,5R,6R)-5-Acetylamino-4-tert-butoxycarbonylamino-6-((1R,2R)-1,2,3-trihydroxy-propyl)-5,6-dihydro-4H-pyran-2-carboxylic acid benzhydryl ester (166830-76-8) → C35H45N5O9 (1053716-70-3)

Guidance literature:

Multi-step reaction with 6 steps

1: aq. NaIO₄ / methanol / 3 h / 23 °C

2: NaClO₂, aq. KH₂PO₄, cyclohexene / 2-methyl-propan-2-ol / 18 h / 23 °C

3: 97 percent / pyridine / dimethylformamide / 3 h / 23 °C

4: tetrahydrofuran / 4 h / 23 °C

5: HCl / dioxane / 0.5 h

6: tetrahydrofuran; dimethylformamide / 18 h / 23 °C

With pyridine; hydrogenchloride; sodium chlorite; sodium periodate; potassium dihydrogenphosphate; cyclohexene; In tetrahydrofuran; 1,4-dioxane; methanol; N,N-dimethyl-formamide; tert-butyl alcohol;

upstream raw materials:

N,N'-bis( tert-butoxycarbonyl)-1H-pyrazole-1-carboxamidine

5-acetamido-4-amino-2,6-anhydro-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic acid

(4S,5R,6R)-5-Acetylamino-4-tert-butoxycarbonylamino-6-((1R,2R)-1,2,3-trihydroxy-propyl)-5,6-dihydro-4H-pyran-2-carboxylic acid

(4S,5R,6R)-5-Acetylamino-4-tert-butoxycarbonylamino-6-((1R,2R)-1,2,3-trihydroxy-propyl)-5,6-dihydro-4H-pyran-2-carboxylic acid benzhydryl ester

Refernces