(5-Aminopentyl)(phenylmethoxy)carbamic acid tert-butyl ester

Base Information

Chemical Name:(5-Aminopentyl)(phenylmethoxy)carbamic acid tert-butyl ester
CAS No.:129245-21-2
Molecular Formula:C17H28N2O3
Molecular Weight:308.421
Hs Code.:
DSSTox Substance ID:DTXSID60450628
Wikidata:Q72440358
ChEMBL ID:CHEMBL1894105
Mol file:129245-21-2.mol

Synonyms:129245-21-2;(5-Aminopentyl)(phenylmethoxy)carbamic acid tert-butyl ester;tert-butyl N-(5-aminopentyl)-N-phenylmethoxycarbamate;tert-butyl 5-aminopentyl(benzyloxy)carbamate;(5-Aminopentyl)(phenylmethoxy)carbamic acid1,1-dimethylethylester;AC-6934;MLS002666817;SCHEMBL8863680;CHEMBL1894105;DTXSID60450628;DHJOLNKVLZRNGD-UHFFFAOYSA-N;HMS3098M06;SMR001554372;N-(5-Aminopentyl)-N-(tert-butoxycarbonyl)-O-benzylhydroxylamine

Suppliers and Price of (5-Aminopentyl)(phenylmethoxy)carbamic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-?(5-?Aminopentyl)?-?N-?(phenylmethoxy)?-?carbamicAcid1,?1-?DimethylethylEster
25mg
$ 215.00

Total 9 raw suppliers

Chemical Property of (5-Aminopentyl)(phenylmethoxy)carbamic acid tert-butyl ester

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.517
Boiling Point:423.605 °C at 760 mmHg
Flash Point:209.989 °C
PSA：64.79000
Density:1.058 g/cm³
LogP:4.18460
Storage Temp.:-20°C Freezer
Solubility.:Dichloromethane, Methanol
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:10
Exact Mass:308.20999276
Heavy Atom Count:22
Complexity:310

Purity/Quality:

99% ^*data from raw suppliers

N-?(5-?Aminopentyl)?-?N-?(phenylmethoxy)?-?carbamicAcid1,?1-?DimethylethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N(CCCCCN)OCC1=CC=CC=C1
Uses N-?(5-?Aminopentyl)?-?N-?(phenylmethoxy)?-?carbamic Acid 1,?1-?Dimethylethyl Ester is an intermediate in synthesizing Deferoxamine-d7 TFA Salt (D228982), a labelled Deferoxamine Mesylate (D228980), which is an iron chelating agent used in therapy for patients with sickle cell diseases and iron overload. Studies suggest that it can exert potential antioxidant neuroprotective effects in stroke patients.

Technology Process of (5-Aminopentyl)(phenylmethoxy)carbamic acid tert-butyl ester

There total 8 articles about (5-Aminopentyl)(phenylmethoxy)carbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 128173-50-2
O-Benzyl-N-(tert-butoxycarbonyl)-N-(4-cyanobutyl)-hydroxylamine

: 129245-21-2
O-benzyl-N-(5-aminopentyl)-N-(tert-butoxycarbonyl)hydroxylamine

Guidance literature:: With ammonia; hydrogen; nickel; In methanol;
DOI:10.1021/jo000050m

Reference yield:

: 6280-87-1
δ-chlorovaleronitrile

: 129245-21-2
O-benzyl-N-(5-aminopentyl)-N-(tert-butoxycarbonyl)hydroxylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / NaH; NaI / dimethylformamide

2: 91 percent / H₂; NH₃ / Raney Ni / methanol

With ammonia; hydrogen; sodium hydride; sodium iodide; nickel; In methanol; N,N-dimethyl-formamide; 1: Substitution / 2: Catalytic hydrogenation;
DOI:10.1021/jo000050m

Reference yield:

: 79722-21-7
tert-butyl N-(benzyloxy)carbamate

: 129245-21-2
O-benzyl-N-(5-aminopentyl)-N-(tert-butoxycarbonyl)hydroxylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / NaH; NaI / dimethylformamide

2: 91 percent / H₂; NH₃ / Raney Ni / methanol

With ammonia; hydrogen; sodium hydride; sodium iodide; nickel; In methanol; N,N-dimethyl-formamide; 1: Substitution / 2: Catalytic hydrogenation;
DOI:10.1021/jo000050m