Technology Process of 3'-<(tert-butyldimethylsilyl)oxy>-3,4,4'-trimethoxy-2,5-bis(benzyloxy)-(Z)-stilbene
There total 10 articles about 3'-<(tert-butyldimethylsilyl)oxy>-3,4,4'-trimethoxy-2,5-bis(benzyloxy)-(Z)-stilbene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 98 percent / diisopropylethylamine / dimethylformamide / 0.5 h
2: 1.) sodium borohydride, 2.) potassium carbonate / 1.) EtOH, 5 min, 2.) reflux, 24 h
3: 99.5 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.17 h
4: 93 percent / pyridinium chlorochromate, sodium acetate / CH2Cl2 / 1 h / Ambient temperature
5: 1.) n-butyllithium / 1.) THF, RT, 10 min, 2.) 10 min
With
sodium tetrahydroborate; n-butyllithium; tetrabutyl ammonium fluoride; sodium acetate; potassium carbonate; N-ethyl-N,N-diisopropylamine; pyridinium chlorochromate;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo00278a023
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) sodium borohydride, 2.) potassium carbonate / 1.) EtOH, 5 min, 2.) reflux, 24 h
2: 99.5 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.17 h
3: 93 percent / pyridinium chlorochromate, sodium acetate / CH2Cl2 / 1 h / Ambient temperature
4: 1.) n-butyllithium / 1.) THF, RT, 10 min, 2.) 10 min
With
sodium tetrahydroborate; n-butyllithium; tetrabutyl ammonium fluoride; sodium acetate; potassium carbonate; pyridinium chlorochromate;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/jo00278a023
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 80 percent / sodium acetate, potassium nitrosodisulfonate (Fremy's salt) / methanol; H2O
2: 98 percent / diisopropylethylamine / dimethylformamide / 0.5 h
3: 1.) sodium borohydride, 2.) potassium carbonate / 1.) EtOH, 5 min, 2.) reflux, 24 h
4: 99.5 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.17 h
5: 93 percent / pyridinium chlorochromate, sodium acetate / CH2Cl2 / 1 h / Ambient temperature
6: 1.) n-butyllithium / 1.) THF, RT, 10 min, 2.) 10 min
With
sodium tetrahydroborate; n-butyllithium; potassium nitrososulfonate; tetrabutyl ammonium fluoride; sodium acetate; potassium carbonate; N-ethyl-N,N-diisopropylamine; pyridinium chlorochromate;
In
tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jo00278a023
