2-Chloro-5-iodonicotinonitrile

Base Information

Chemical Name:2-Chloro-5-iodonicotinonitrile
CAS No.:766515-34-8
Molecular Formula:C₆H₂ClIN₂
Molecular Weight:264.453
Hs Code.:2933399090
DSSTox Substance ID:DTXSID30694774
Wikidata:Q72452599
Mol file:766515-34-8.mol

Synonyms:2-Chloro-5-iodonicotinonitrile;766515-34-8;2-CHLORO-5-IODOPYRIDINE-3-CARBONITRILE;2-CHLORO-5-IODO-3-PYRIDINECARBONITRILE;MFCD09909360;SCHEMBL4064950;DTXSID30694774;FYHRQFFVACXNTB-UHFFFAOYSA-N;AB3542;AKOS015150930;AM87191;AC-25199;CS-12091;SY037250;CS-0186611;FT-0698949;A850839;2-Chloro-5-iodo-3-pyridinecarbonitrile

Suppliers and Price of 2-Chloro-5-iodonicotinonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-Chloro-5-iodonicotinonitrile
250 mg
$ 61.00

SynQuest Laboratories
2-Chloro-5-iodonicotinonitrile
1 g
$ 146.00

Matrix Scientific
2-Chloro-5-iodonicotinonitrile 95%
5g
$ 1453.00

Matrix Scientific
2-Chloro-5-iodonicotinonitrile 95%
1g
$ 469.00

Crysdot
2-Chloro-5-iodonicotinonitrile 95+%
1g
$ 120.00

Crysdot
2-Chloro-5-iodonicotinonitrile 95+%
5g
$ 360.00

Crysdot
2-Chloro-5-iodonicotinonitrile 95+%
10g
$ 590.00

Chemenu
2-Chloro-5-iodonicotinonitrile 95%
10g
$ 552.00

Chemenu
2-Chloro-5-iodonicotinonitrile 95%
5g
$ 337.00

Chemcia Scientific
2-Chloro-5-iodo-nicotinonitrile ＞97%
1 G
$ 275.00

Total 18 raw suppliers

Chemical Property of 2-Chloro-5-iodonicotinonitrile

Chemical Property:

PSA：36.68000
Density:2.13g/cm³
LogP:2.21128
Storage Temp.:2-8°C(protect from light)
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:263.89512
Heavy Atom Count:10
Complexity:164

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-5-iodonicotinonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=NC(=C1C#N)Cl)I

Technology Process of 2-Chloro-5-iodonicotinonitrile

There total 3 articles about 2-Chloro-5-iodonicotinonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 766515-33-7
3-cyano-2-hydroxy-5-iodopyridine

: 766515-34-8
2-chloro-5-iodopyridine-3-carbonitrile

Guidance literature:: With trichlorophosphate; Heating;
DOI:10.1016/j.tetlet.2004.07.022

Reference yield:

: 20577-27-9,95907-03-2
2-hydroxy-3-cyanopyridine

: 766515-34-8
2-chloro-5-iodopyridine-3-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / iodine; potassium carbonate / dimethylformamide / 60 °C

2: 80 percent / phosphorus oxychloride / Heating

With iodine; potassium carbonate; trichlorophosphate; In N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2004.07.022

Reference yield:

: 6602-54-6
2-chloro-3-pyridinecarbonitrile

: 766515-34-8
2-chloro-5-iodopyridine-3-carbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / acetic acid / Heating

2: 50 percent / iodine; potassium carbonate / dimethylformamide / 60 °C

3: 80 percent / phosphorus oxychloride / Heating

With iodine; potassium carbonate; acetic acid; trichlorophosphate; In N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2004.07.022