6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine

Base Information

Chemical Name:6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine
CAS No.:677297-51-7
Molecular Formula:C18H14N6O2
Molecular Weight:346.348
Hs Code.:
UNII:7ACH1U1E2M
DSSTox Substance ID:DTXSID20218009
Nikkaji Number:J2.417.450F
Wikidata:Q27088972
Pharos Ligand ID:NQR8K76TB5J3
Metabolomics Workbench ID:149514
ChEMBL ID:CHEMBL230011
Mol file:677297-51-7.mol

Synonyms:3-(2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl)phenol;TG100-115

Suppliers and Price of 6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
TG100-115
10mg
$ 120.00

Medical Isotopes, Inc.
TG100-115
50 mg
$ 1225.00

DC Chemicals
TG100-115 >98%
1 g
$ 1600.00

DC Chemicals
TG100-115 >98%
100 mg
$ 400.00

Crysdot
TG100-115 98+%
50mg
$ 397.00

Crysdot
TG100-115 98+%
10mg
$ 139.00

Crysdot
TG100-115 98+%
5mg
$ 88.00

ChemScene
TG100-115 99.31%
5mg
$ 96.00

ChemScene
TG100-115 99.31%
50mg
$ 468.00

Biosynth Carbosynth
6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine
25 mg
$ 100.00

Total 36 raw suppliers

Chemical Property of 6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine

Chemical Property:

Boiling Point:699.6±65.0 °C(Predicted)
PKA:8.54±0.10(Predicted)
PSA：144.79000
Density:1.516±0.06 g/cm3(Predicted)
LogP:2.84070
Solubility.:insoluble in H2O; insoluble in EtOH; ≥3.46 mg/mL in DMSO
XLogP3:1.7
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:2
Exact Mass:346.11782371
Heavy Atom Count:26
Complexity:483

Purity/Quality:

99%, ^*data from raw suppliers

TG100-115 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)O)C2=NC3=C(N=C(N=C3N=C2C4=CC(=CC=C4)O)N)N
Recent ClinicalTrials:Safety of TG100-115 for Heart Attack Treated With Angioplasty
Uses TG100-115 is a potent and selective phosphoinositide 3-kinase gamma/delta (PI3Kγ/δ) inhibitor. It can provide potent cardioprotection, reduce infarct development, and preserve myocardial function.

Technology Process of 6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine

There total 2 articles about 6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.3%