2-(TRIFLUOROMETHYL)-1,3-THIAZOLE-4-CARBALDEHYDE

Base Information

• Chemical Name: 2-(TRIFLUOROMETHYL)-1,3-THIAZOLE-4-CARBALDEHYDE
• CAS No.: 133046-48-7
• Molecular Formula: C₅H₂F₃NOS
• Molecular Weight: 181.138
• Hs Code.: 2934100090
• Mol file: 133046-48-7.mol

Synonyms:2-(Trifluoromethyl)-1,3-thiazole-4-carbaldehyde;

Chemical Property of 2-(TRIFLUOROMETHYL)-1,3-THIAZOLE-4-CARBALDEHYDE

Chemical Property:

• Vapor Pressure: 3.14mmHg at 25°C
• Refractive Index: 1.499
• Boiling Point: 154.7 °C at 760 mmHg
• PKA: -2.41±0.10(Predicted)
• Flash Point: 47.4 °C
• PSA: 58.20000
• Density: 1.544 g/cm³
• LogP: 1.97440

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(Trifluoromethyl)thiazole-4-carbaldehyde 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(TRIFLUOROMETHYL)-1,3-THIAZOLE-4-CARBALDEHYDE

There total 1 articles about 2-(TRIFLUOROMETHYL)-1,3-THIAZOLE-4-CARBALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

Ethyl 2-(trifluoromethyl)thiazole-4-carboxylate (133046-46-5) → 2-(trifluoromethyl)-1,3-thiazole-4-carbaldehyde (133046-48-7) + (2-(trifluoromethyl)-1,3-thiazol-4-yl)methanol (133046-47-6)

Guidance literature:

With diisobutylaluminium hydride; In dichloromethane; at -78 ℃; for 1h;

upstream raw materials:

Ethyl 2-(trifluoromethyl)thiazole-4-carboxylate

Refernces