((2R,6S)-6-Methoxy-2-phenyl-3,6-dihydro-2H-pyran-4-yloxy)-trimethyl-silane

Base Information

• Chemical Name: ((2R,6S)-6-Methoxy-2-phenyl-3,6-dihydro-2H-pyran-4-yloxy)-trimethyl-silane
• CAS No.: 85612-97-1
• Molecular Formula: C₁₅H₂₂O₃Si
• Molecular Weight: 278.423
• Mol file: 85612-97-1.mol

Synonyms:

Chemical Property of ((2R,6S)-6-Methoxy-2-phenyl-3,6-dihydro-2H-pyran-4-yloxy)-trimethyl-silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ((2R,6S)-6-Methoxy-2-phenyl-3,6-dihydro-2H-pyran-4-yloxy)-trimethyl-silane

There total 2 articles about ((2R,6S)-6-Methoxy-2-phenyl-3,6-dihydro-2H-pyran-4-yloxy)-trimethyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

danishefsky's diene (54125-02-9) + benzaldehyde (100-52-7) → ((2R,6S)-6-Methoxy-2-phenyl-3,6-dihydro-2H-pyran-4-yloxy)-trimethyl-silane (85612-97-1) + ((2R,6R)-6-Methoxy-2-phenyl-3,6-dihydro-2H-pyran-4-yloxy)-trimethyl-silane

Guidance literature:

tris(6,6,7,7,8,8-heptafluoro-2,2-dimethyl-3,5-octadionato)europium(III); In chloroform-d1; for 48h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1021/ja00349a064

Reference yield:

danishefsky's diene (54125-02-9) + benzaldehyde (100-52-7) → ((2R,6S)-6-Methoxy-2-phenyl-3,6-dihydro-2H-pyran-4-yloxy)-trimethyl-silane (85612-97-1)

Guidance literature:

With PF6; In chloroform; for 24h; Mechanism; Ambient temperature; other, enantiomerically pure chelating complexes; asymmetric induction was also investigated;

DOI:10.1016/S0040-4039(00)72712-2

Reference yield:

((2R,6S)-6-Methoxy-2-phenyl-3,6-dihydro-2H-pyran-4-yloxy)-trimethyl-silane (85612-97-1) → 2-phenyl-2,3-dihydropyran-4-one (40989-96-6)

Guidance literature:

With trifluoroacetic acid;

DOI:10.1016/S0040-4039(00)72712-2

upstream raw materials:

danishefsky's diene

benzaldehyde

Downstream raw materials:

2-phenyl-2,3-dihydropyran-4-one

Refernces

• 1、 Bednarski, M.,Danishefsky, S.. "Mild Lewis Acid Catalysis: Eu(fod)3-Mediated Hetero-Diels-Alder Reaction". . p. 3716 - 3717. Retrieved 2007/10/02.