(-)-N-[4-(2,2-Dimethylpropanoyl)-5-[[2-(ethylamino)ethanesulfonamido]methyl]-5-phenyl-4,5-dihydro-1,3,4-thiadiazol-2-yl]-2,2-dimethylpropanamide

Base Information

Chemical Name:(-)-N-[4-(2,2-Dimethylpropanoyl)-5-[[2-(ethylamino)ethanesulfonamido]methyl]-5-phenyl-4,5-dihydro-1,3,4-thiadiazol-2-yl]-2,2-dimethylpropanamide
CAS No.:910634-41-2
Molecular Formula:C₂₃H₃₇N₅O₄S₂
Molecular Weight:511.71
Hs Code.:
Mol file:910634-41-2.mol

(-)-N-[4-(2,2-Dimethylpropanoyl)-5-[[2-(ethylamino)ethanesulfonamido]methyl]-5-phenyl-4,5-dihydro-1,3,4-thiadiazol-2-yl]-2,2-dimethylpropanamide

Synonyms:Litronesib;Litronesib (USAN/INN);UNII-6611F8KYCV;Litronesib [USAN];

Suppliers and Price of (-)-N-[4-(2,2-Dimethylpropanoyl)-5-[[2-(ethylamino)ethanesulfonamido]methyl]-5-phenyl-4,5-dihydro-1,3,4-thiadiazol-2-yl]-2,2-dimethylpropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
Litronesib >98%
1 g
$ 3060.00

Crysdot
Litronesib 98+%
100mg
$ 1459.00

Crysdot
Litronesib 98+%
10mg
$ 347.00

Crysdot
Litronesib 98+%
5mg
$ 243.00

Crysdot
Litronesib 98+%
50mg
$ 1042.00

ChemScene
Litronesib 99.59%
50mg
$ 840.00

ChemScene
Litronesib 99.59%
10mg
$ 228.00

ChemScene
Litronesib 99.59%
100mg
$ 1440.00

ChemScene
Litronesib 99.59%
5mg
$ 132.00

Biosynth Carbosynth
(-)-N-[4-(2,2-Dimethylpropanoyl)-5-[[2-(ethylamino)ethanesulfonamido]methyl]-5-phenyl-4,5-dihydro-1,3,4-thiadiazol-2-yl]-2,2-dimethylpropanamide
25 mg
$ 405.00

Total 10 raw suppliers

Chemical Property of (-)-N-[4-(2,2-Dimethylpropanoyl)-5-[[2-(ethylamino)ethanesulfonamido]methyl]-5-phenyl-4,5-dihydro-1,3,4-thiadiazol-2-yl]-2,2-dimethylpropanamide

Chemical Property:

PKA:9.47±0.40(Predicted)
PSA：157.14000
Density:1.23 g/cm³
LogP:4.49950

Purity/Quality:

99%, ^*data from raw suppliers

Litronesib >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Litronesib is a selective allosteric kinesin Eg5 inhibitor in patients with advanced cancer.

Technology Process of (-)-N-[4-(2,2-Dimethylpropanoyl)-5-[[2-(ethylamino)ethanesulfonamido]methyl]-5-phenyl-4,5-dihydro-1,3,4-thiadiazol-2-yl]-2,2-dimethylpropanamide

There total 14 articles about (-)-N-[4-(2,2-Dimethylpropanoyl)-5-[[2-(ethylamino)ethanesulfonamido]methyl]-5-phenyl-4,5-dihydro-1,3,4-thiadiazol-2-yl]-2,2-dimethylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%