Diazo Biotin-PEG3-Azide

Base Information

Chemical Name:Diazo Biotin-PEG3-Azide
CAS No.:1339202-33-3
Molecular Formula:C₃₃H₄₅N₉O₇S
Molecular Weight:711.842
Hs Code.:
Mol file:1339202-33-3.mol

Synonyms:

Suppliers and Price of Diazo Biotin-PEG3-Azide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
DiazoBiotin-PEG3-azide
1mg
$ 45.00

Chem-Impex
Diazobiotinazide
5MG
$ 419.33

BroadPharm
DiazoBiotin-PEG3-azide 95%
50 MG
$ 995.00

BroadPharm
DiazoBiotin-PEG3-azide 95%
25 MG
$ 679.00

BroadPharm
DiazoBiotin-PEG3-azide 95%
5 MG
$ 239.00

Total 4 raw suppliers

Chemical Property of Diazo Biotin-PEG3-Azide

Chemical Property:

Storage Temp.:-20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

DiazoBiotin-PEG3-azide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description Diazo Biotin-PEG3-azide is useful for introducing a biotin moiety to alkyne-containing biomolecules using Cu(I)-catalyzed Click Chemistry. The hydrophilic spacer arm provides better solubility to the labeled molecules in aqueous media. Diazo allows efficient release of captured biotinylated molecules from streptavidin using sodium dithionite (Na2S2O4).
Uses Azo biotin-azide is a linker that contains a biotin moiety connected to an azide group through a spacer arm containing a diazo group that can be cleaved with 50 mM sodium dithionite solution. The biotin can be captured by streptavidin and the azide can react with terminal or strained alkynes.

Technology Process of Diazo Biotin-PEG3-Azide

There total 2 articles about Diazo Biotin-PEG3-Azide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 875770-34-6
N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]biotinamide

: 1339202-33-3
4-((E)-(5-(2-azidoethyl)-2-hydroxyphenyl)diazenyl)-N-(13-oxo-17-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: water; triphenylphosphine / tetrahydrofuran / 12 h / 20 °C / Inert atmosphere

2: N,N-dimethyl-formamide / 12 h / 20 °C / Inert atmosphere

With water; triphenylphosphine; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1002/asia.201100306