1-(2-Fluoro-4-nitrophenyl)pyrrolidine

Base Information

Chemical Name:1-(2-Fluoro-4-nitrophenyl)pyrrolidine
CAS No.:385380-74-5
Molecular Formula:C10H11FN2O2
Molecular Weight:210.208
Hs Code.:2933990090
DSSTox Substance ID:DTXSID20386772
Nikkaji Number:J2.402.514D
Wikidata:Q72475398
Mol file:385380-74-5.mol

Synonyms:1-(2-fluoro-4-nitrophenyl)pyrrolidine;385380-74-5;3-fluoro-4-(pyrrolidin-1-yl)nitrobenzene;Pyrrolidine, 1-(2-fluoro-4-nitrophenyl)-;MFCD02633454;Cambridge id 5842403;Oprea1_087961;SCHEMBL4921368;DTXSID20386772;SMKXLBISYVJESG-UHFFFAOYSA-N;STL414717;AKOS003286224;AC-8456;AM86925;CS-11022;SY002977;CS-0452054;FT-0737471;A21946;SR-01000221612;SR-01000221612-1

Suppliers and Price of 1-(2-Fluoro-4-nitrophenyl)pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(2-Fluoro-4-nitrophenyl)pyrrolidine
500mg
$ 65.00

TRC
1-(2-Fluoro-4-nitrophenyl)pyrrolidine
100mg
$ 45.00

Oakwood
1-(2-Fluoro-4-nitrophenyl)pyrrolidine 97%
25g
$ 149.00

Oakwood
1-(2-Fluoro-4-nitrophenyl)pyrrolidine 97%
1g
$ 19.00

Matrix Scientific
3-Fluoro-4-(pyrrolidin-1-yl)nitrobenzene
1g
$ 1143.00

Crysdot
1-(2-Fluoro-4-nitrophenyl)pyrrolidine 97%
100g
$ 428.00

Chemenu
3-Fluoro-4-(pyrrolidin-1-yl)nitrobenzene 97%
100g
$ 400.00

American Custom Chemicals Corporation
1-(2-FLUORO-4-NITROPHENYL)PYRROLIDINE 95.00%
5MG
$ 503.31

Alichem
1-(2-Fluoro-4-nitrophenyl)pyrrolidine
100g
$ 432.28

Alichem
1-(2-Fluoro-4-nitrophenyl)pyrrolidine
25g
$ 157.50

Total 18 raw suppliers

Chemical Property of 1-(2-Fluoro-4-nitrophenyl)pyrrolidine

Chemical Property:

Vapor Pressure:6.32E-05mmHg at 25°C
Refractive Index:1.576
Boiling Point:345.1 °C at 760 mmHg
Flash Point:162.5 °C
PSA：49.06000
Density:1.313g/cm³
LogP:2.92230
Storage Temp.:2-8°C
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:210.08045576
Heavy Atom Count:15
Complexity:238

Purity/Quality:

97% ^*data from raw suppliers

1-(2-Fluoro-4-nitrophenyl)pyrrolidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)C2=C(C=C(C=C2)[N+](=O)[O-])F

Technology Process of 1-(2-Fluoro-4-nitrophenyl)pyrrolidine

There total 3 articles about 1-(2-Fluoro-4-nitrophenyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1-(2-fluoro-4-nitro-phenyl)-pyrrolidine 1-oxide

: 385380-74-5
3-fluoro-1-nitro-4-pyrrolidinobenzene

Guidance literature:: With copper(l) iodide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 35 - 40 ℃; for 3h;
DOI:10.1016/j.tet.2006.10.031

Reference yield: 76.0%

: 123-75-1
pyrrolidine

: 369-34-6
3,4-difluoronitrobenzene

: 385380-74-5
3-fluoro-1-nitro-4-pyrrolidinobenzene

Guidance literature:: With triethylamine; In ethyl acetate; at 20 ℃;

Reference yield:

: 367-11-3
ortho-difluorobenzene

: 385380-74-5
3-fluoro-1-nitro-4-pyrrolidinobenzene

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / HNO₃; H₂SO₄ / 6 h / 60 - 70 °C

2: 60 percent / dimethylsulfoxide / 2 h / Heating

With sulfuric acid; nitric acid; In dimethyl sulfoxide;
DOI:10.1007/s11172-006-0406-9