C₃₀H₂₉N₅O₄

Base Information

• Chemical Name: C₃₀H₂₉N₅O₄
• CAS No.: 431052-60-7
• Molecular Formula: C₃₀H₂₉N₅O₄
• Molecular Weight: 523.591
• Mol file: 431052-60-7.mol

Synonyms:

Chemical Property of C₃₀H₂₉N₅O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₂₉N₅O₄

There total 16 articles about C₃₀H₂₉N₅O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

C43H47N5O6 (431052-71-0) → C30H29N5O4 (431052-60-7)

Guidance literature:

With methoxybenzene; trifluoroacetic acid;

DOI:10.1016/j.bmcl.2013.06.028

Reference yield:

pyridine-2-carbaldehyde (1121-60-4) → C30H29N5O4 (431052-60-7)

Guidance literature:

Multi-step reaction with 11 steps

1: N,N',N'-trimethylenediamine; n-butyllithium / tetrahydrofuran; hexane; cyclohexane

2: sodium chlorite; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene / tert-butyl alcohol; acetonitrile; water

3: caesium carbonate / N,N-dimethyl-formamide

4: 3-chloro-benzenecarboperoxoic acid / dichloromethane

5: bis-triphenylphosphine-palladium(II) chloride; copper(II) oxide / N,N-dimethyl-formamide / 110 °C

6: trifluoroacetic anhydride / N,N-dimethyl-formamide

7: sodium hydroxide; water / tetrahydrofuran

8: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 1-hydroxy-7-aza-benzotriazole / N,N-dimethyl-formamide

9: triethylamine / dichloromethane

10: bis-triphenylphosphine-palladium(II) chloride; copper(II) oxide / N,N-dimethyl-formamide / 110 °C

11: trifluoroacetic acid; methoxybenzene

With dmap; bis-triphenylphosphine-palladium(II) chloride; sodium chlorite; n-butyllithium; 1-hydroxy-7-aza-benzotriazole; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene; water; caesium carbonate; N,N',N'-trimethylenediamine; methoxybenzene; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic acid; trifluoroacetic anhydride; copper(II) oxide; sodium hydroxide; In tetrahydrofuran; hexane; dichloromethane; cyclohexane; water; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;

DOI:10.1016/j.bmcl.2013.06.028

Reference yield:

3-(tributylstannyl)picolinaldehyde (431052-64-1) → C30H29N5O4 (431052-60-7)

Guidance literature:

Multi-step reaction with 10 steps

1: sodium chlorite; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene / tert-butyl alcohol; acetonitrile; water

2: caesium carbonate / N,N-dimethyl-formamide

3: 3-chloro-benzenecarboperoxoic acid / dichloromethane

4: bis-triphenylphosphine-palladium(II) chloride; copper(II) oxide / N,N-dimethyl-formamide / 110 °C

5: trifluoroacetic anhydride / N,N-dimethyl-formamide

6: sodium hydroxide; water / tetrahydrofuran

7: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 1-hydroxy-7-aza-benzotriazole / N,N-dimethyl-formamide

8: triethylamine / dichloromethane

9: bis-triphenylphosphine-palladium(II) chloride; copper(II) oxide / N,N-dimethyl-formamide / 110 °C

10: trifluoroacetic acid; methoxybenzene

With dmap; bis-triphenylphosphine-palladium(II) chloride; sodium chlorite; 1-hydroxy-7-aza-benzotriazole; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene; water; caesium carbonate; methoxybenzene; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic acid; trifluoroacetic anhydride; copper(II) oxide; sodium hydroxide; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;

DOI:10.1016/j.bmcl.2013.06.028

upstream raw materials:

pyridine-2-carbaldehyde

3-(tributylstannyl)picolinaldehyde

C₁₉H₃₃NO₃Sn

C₂₃H₂₈N₂O₆