4-[(4-METHYLPHENYL)SULFANYL]ANILINE

Base Information

• Chemical Name: 4-[(4-METHYLPHENYL)SULFANYL]ANILINE
• CAS No.: 22865-52-7
• Molecular Formula: C13H13 N S
• Molecular Weight: 215.319
• Hs Code.: 2930909090
• Mol file: 22865-52-7.mol

Synonyms:Aniline,p-(p-tolylthio)- (6CI,8CI); 4-(4-Methylphenylsulfanyl)aniline;4-(p-Tolylthio)aniline; 4-Amino-4'-methyldiphenyl sulfide; 4-Aminophenyl4-methylphenyl sulfide; 4-[(4-Methylphenyl)thio]aniline; p-Aminophenyl p-tolylsulfide

Chemical Property of 4-[(4-METHYLPHENYL)SULFANYL]ANILINE

Chemical Property:

• Vapor Pressure: 1.79E-06mmHg at 25°C
• Melting Point: 73-75,5°C
• Boiling Point: 395.8°Cat760mmHg
• Flash Point: 193.2°C
• PSA: 51.32000
• Density: 1.17g/cm³
• LogP: 4.30960

Purity/Quality:

99%, ^*data from raw suppliers

4-[(4-Methylphenyl)sulfanyl]aniline >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-[(4-METHYLPHENYL)SULFANYL]ANILINE

There total 30 articles about 4-[(4-METHYLPHENYL)SULFANYL]ANILINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

aniline (62-53-3) + para-thiocresol (106-45-6) → 4-amino-4'-methyldiphenylsulphide (22865-52-7)

Guidance literature:

With 5-ethyl-1,3,7,8-tetramethylalloxazinium triflate; iodine; In acetonitrile; at 20 - 60 ℃; for 20h; Reagent/catalyst; Solvent; Temperature;

Reference yield: 96.0%

para-thiocresol (106-45-6) + p-aminoiodobenzene (540-37-4) → 4-amino-4'-methyldiphenylsulphide (22865-52-7)

Guidance literature:

With (R)-1-[(S_P)-2-(dicyclohexylphosphino)ferrocenyl]ethyldi-tert-butylphosphine; palladium diacetate; lithium hexamethyldisilazane; In 1,2-dimethoxyethane; at 90 ℃; Inert atmosphere;

DOI:10.1021/jo802594d

Reference yield: 95.0%

aniline (62-53-3) + toluene-4-sulfonic acid hydrazide (1576-35-8) → 4-amino-4'-methyldiphenylsulphide (22865-52-7)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; propylene glycol dimethyl ether dimer; at 100 ℃; for 12h; Schlenk technique;

DOI:10.1016/j.tet.2020.131646

upstream raw materials:

4-nitrophenyl 4-methylphenyl sulfide

sodium p-thiocresolate

4-chlorobenzonitrile

p-toluene sulfinic acid

Downstream raw materials:

(4-cyanophenyl)(4-methylphenyl)sulfide

N-[4-(p-tolylthio)phenyl]acetamide