(5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER

Base Information

• Chemical Name: (5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER
• CAS No.: 914349-79-4
• Molecular Formula: C₉H₁₂BrN₃O₂
• Molecular Weight: 274.117
• Hs Code.: 2933990090
• Mol file: 914349-79-4.mol

Synonyms:(5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER;(5-BROMOPYRAZINYL)CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER;N-Boc-2-Amino-5-bromopyrazine;2-Amino-5-bromopyrazine, 2-BOC;CarbaMicacid,(5-broMopyrazinyl)-,1,1-diMethylethylester;2-Amino-5-bromopyrazine, 2-BOC protected;tert-Butyl (5-bromopyrazin-2-yl)carbamate, 2-Bromo-5-[(tert-butoxycarbonyl)amino]-1,4-diazine

Chemical Property of (5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER

Chemical Property:

• Vapor Pressure: 0.00155mmHg at 25°C
• Refractive Index: 1.576
• Boiling Point: 295.2 °C at 760 mmHg
• Flash Point: 132.3 °C
• PSA: 64.11000
• Density: 1.513 g/cm³
• LogP: 2.65910
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

N-Boc-2-amino-5-bromopyrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (5-BROMOPYRAZIN-2-YL) CARBAMIC ACID TERT-BUTYL ESTER can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Technology Process of (5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER

There total 1 articles about (5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.2%

5-amino-2-bromopyrazine (59489-71-3) + di-tert-butyl dicarbonate (24424-99-5) → tert-butyl N-(5-bromopyrazin-2-yl)carbamate (914349-79-4)

Guidance literature:

With dmap; In dichloromethane; at 0 - 20 ℃;

upstream raw materials:

5-amino-2-bromopyrazine

di-tert-butyl dicarbonate