Technology Process of (1S,2S,3R,4S,5R,6R)-3,5-Bis-benzyloxy-4,6-bis-[((E)-propenyl)oxy]-cyclohexane-1,2-diol
There total 20 articles about (1S,2S,3R,4S,5R,6R)-3,5-Bis-benzyloxy-4,6-bis-[((E)-propenyl)oxy]-cyclohexane-1,2-diol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: NaH / dimethylformamide / 20 °C
2: 64 percent / toluene-p-sulphonic acid / 10percent Pd-C / ethanol; H2O / 24 h / 95 °C
3: 900 mg / toluene-p-sulphonic acid / acetone / 6 h / 20 °C
4: NaH / dimethylformamide
5: 1M HCl / acetone / 0.5 h / Heating
6: pyridine / 10 h / 20 °C
7: NaOH / methanol
8: potassium tert-butoxide / dimethylsulfoxide
With
pyridine; hydrogenchloride; sodium hydroxide; potassium tert-butylate; sodium hydride; toluene-4-sulfonic acid;
palladium on activated charcoal;
In
methanol; ethanol; water; dimethyl sulfoxide; N,N-dimethyl-formamide; acetone;
DOI:10.1016/S0008-6215(00)90549-4
- Guidance literature:
-
Multi-step reaction with 6 steps
1: NaH / dimethylformamide / 20 °C
2: 64 percent / toluene-p-sulphonic acid / 10percent Pd-C / ethanol; H2O / 24 h / 95 °C
3: 900 mg / toluene-p-sulphonic acid / acetone / 6 h / 20 °C
4: NaH / dimethylformamide
5: 1M HCl / acetone / 0.5 h / Heating
6: 120 mg / potassium tert-butoxide / dimethylsulfoxide / 5 h / 50 °C
With
hydrogenchloride; potassium tert-butylate; sodium hydride; toluene-4-sulfonic acid;
palladium on activated charcoal;
In
ethanol; water; dimethyl sulfoxide; N,N-dimethyl-formamide; acetone;
DOI:10.1016/S0008-6215(00)90549-4
