Dihydrocinchonamine

Base Information

• Chemical Name: Dihydrocinchonamine
• CAS No.: 10283-68-8
• Molecular Formula: C₁₉H₂₆N₂O
• Molecular Weight: 298.428
• Hs Code.: 2933990090
• Mol file: 10283-68-8.mol

Synonyms:Cinchonamine,18,19-dihydro- (8CI); Cinchonamine, dihydro- (7CI); Dihydrocinchonamin;Dihydrocinchonamine

Chemical Property of Dihydrocinchonamine

Chemical Property:

• PSA: 39.26000
• LogP: 3.43350

Purity/Quality:

98%,99%, ^*data from raw suppliers

Dihydrocinchonamine ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Dihydrocinchonamine

There total 10 articles about Dihydrocinchonamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Dihydrocinchonamin (10283-68-8)

Guidance literature:

With lithium aluminium tetrahydride; diethyl ether;

DOI:10.1093/jmt/38.4.321

Reference yield:

(+)-cinchonamine (482-28-0) → Dihydrocinchonamin (10283-68-8)

Guidance literature:

With methanol; palladium-barium carbonate; Hydrogenation;

DOI:10.1002/hlca.19500330124

Reference yield:

quinamine (464-85-7,464-86-8,77549-88-3) → Dihydrocinchonamin (10283-68-8)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄; diethyl ether / Erhitzen des Reaktionsprodukts

2: palladium/BaCO₃; methanol / Hydrogenation

With methanol; lithium aluminium tetrahydride; palladium-barium carbonate; diethyl ether;

DOI:10.1002/hlca.19500330124

upstream raw materials:

(+)-cinchonamine

quinamine

Downstream raw materials:

(4R)-4,17-cyclo-corynanium; toluene-4-sulfonate