4',5,7-Trihydroxy-6-prenylflavone

Base Information

• Chemical Name: 4',5,7-Trihydroxy-6-prenylflavone
• CAS No.: 68097-13-2
• Molecular Formula: C20H18O5
• Molecular Weight: 338.36
• Hs Code.: 2932999099

Synonyms:4',5,7-trihydroxy-6-prenylflavone;4',5,7-trihydroxy-6-methylflavone;5,7,4'-Trihydroxy-6-methyl-flavon;6-prenylapigenin;5,7,4'-Trihydroxy-6-methylflavone;6-Methylapigenin;4',5,7-trihydroxy-6-C-prenylflavone;

Chemical Property of 4',5,7-Trihydroxy-6-prenylflavone

Chemical Property:

• PSA: 90.90000
• LogP: 4.08550
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

4',5,7-Trihydroxy-6-Prenylflavone 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4',5,7-Trihydroxy-6-prenylflavone

There total 16 articles about 4',5,7-Trihydroxy-6-prenylflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.7%

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one (520-36-5) + 3,3-dimethylallyl diphosphate triammonium salt (1186-30-7,45126-99-6,69382-61-2) → 6-prenylapigenin (68097-13-2)

Guidance literature:

With fungal prenyltransferase AnaPT; calcium chloride; In dimethyl sulfoxide; glycerol; at 37 ℃; for 16h; pH=7.5; Time; Kinetics; Enzymatic reaction;

DOI:10.1021/acs.jnatprod.5b00422

Reference yield:

dimethylallyl diphosphate (358-72-5) + 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one (520-36-5) → 6-prenylapigenin (68097-13-2)

Guidance literature:

With magnesium chloride; In aq. buffer; at 30 ℃; for 12h;

DOI:10.1002/cbic.201402160

Reference yield:

4'-hydroxy-5,7-di(methoxymethoxy)-6-C-prenylflavone (249640-51-5) → 6-prenylapigenin (68097-13-2)

Guidance literature:

With hydrogenchloride; In methanol; for 0.25h; Heating;

upstream raw materials:

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

prenyl bromide

2-methyl-3-buten-2-ol

4'-hydroxy-5,7-di(methoxymethoxy)-6-C-prenylflavone

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