(R)-(-)-1,2-Diamino-1-phenylethane

Base Information

• Chemical Name: (R)-(-)-1,2-Diamino-1-phenylethane
• CAS No.: 62779-69-5
• Molecular Formula: C8H12N2
• Molecular Weight: 136.197
• Mol file: 62779-69-5.mol

Synonyms:(R)-1-Phenyl-aethylendiamin;(R)-1-phenyletylenediamine;(R)-1-phenylethane-1,2-diamine;(R)-1-phenyl-ethanediyldiamine;(R)-2-Phenylethylenediamine;(R)-1-Phenyl-aethandiyldiamin;

Chemical Property of (R)-(-)-1,2-Diamino-1-phenylethane

Chemical Property:

• PSA: 52.04000
• LogP: 2.04570

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-(-)-1,2-Diamino-1-phenylethane

There total 9 articles about (R)-(-)-1,2-Diamino-1-phenylethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenylglyoxime (4589-97-3) → (R)-1,2-Diamino-1-phenylethane (62779-69-5)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂ / Pd-C / acetic acid

2: aq. HBr / acetic acid

With hydrogen bromide; hydrogen; palladium on activated charcoal; In acetic acid;

Reference yield:

α-bromoacetophenone (70-11-1) → (R)-1,2-Diamino-1-phenylethane (62779-69-5)

Guidance literature:

Multi-step reaction with 4 steps

1: NH₂OH

2: H₂ / Pd-C / acetic acid

3: aq. HBr / acetic acid

With hydrogen bromide; hydrogen; hydroxylamine; palladium on activated charcoal; In acetic acid;

Reference yield:

(R)-Phenylglycine methyl ester (24461-61-8) → (R)-1,2-Diamino-1-phenylethane (62779-69-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / aq. NH₃ / toluene

2: 45 percent / LiAlH₄ / tetrahydrofuran

With ammonium hydroxide; lithium aluminium tetrahydride; In tetrahydrofuran; toluene;

DOI:10.1016/S0040-4039(00)02007-4

upstream raw materials:

1,2-diaminophenylethane

D-phenylglycine methyl ester hydrochloride

(R)-Phenylglycine methyl ester

ethyl (3S)-3-amino-3-phenylpropionate

Downstream raw materials:

(R)-1,2-Di(acetylamino)-1-phenylethane

(1R)-[N,N'-bis(2'-hydroxybenzylidene)]-1-phenyl-1,2-diaminoethane

(R)-5-phenyl-2,3-piperazinedione

(R)-3-phenyl[1,2,5]thiadiazolidine-1,1-dioxide