4-Fluoro-2-methoxyaniline

Base Information

Chemical Name:4-Fluoro-2-methoxyaniline
CAS No.:450-91-9
Molecular Formula:C7H8FNO
Molecular Weight:141.145
Hs Code.:2922299090
European Community (EC) Number:814-457-6
DSSTox Substance ID:DTXSID70543136
Wikidata:Q72489881
Mol file:450-91-9.mol

Synonyms:4-Fluoro-2-methoxyaniline;450-91-9;2-Methoxy-4-fluoroaniline;4-fluoro-2-methoxy-aniline;4-Fluoro-o-anisidine;MFCD00077536;2-AMINO-5-FLUOROANISOLE;Benzenamine, 4-fluoro-2-methoxy-;4-FLUORO-2-METHOXYBENZENAMINE;4-fluoro-2-methoxyphenylamine;SCHEMBL455982;4-fluoro-2-(methyloxy)aniline;4-Fluoro-2-methoxy-phenylamine;(4-Fluoro-2-methoxyphenyl)amine;DTXSID70543136;BNRRMRUVYDETQC-UHFFFAOYSA-N;BCP11916;CS-B0927;AKOS000149628;CCG-325856;GS-4323;MB00562;AC-28647;SY026829;AM20050535;F1003;EN300-31570;J-515338;Z240869728

Suppliers and Price of 4-Fluoro-2-methoxyaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-?Fluoro-?2-?methoxyaniline
25g
$ 1185.00

TCI Chemical
4-Fluoro-2-methoxyaniline >98.0%(GC)(T)
1g
$ 88.00

TCI Chemical
4-Fluoro-2-methoxyaniline >98.0%(GC)(T)
5g
$ 263.00

SynQuest Laboratories
4-Fluoro-2-methoxyaniline 97%
100 g
$ 184.00

SynQuest Laboratories
4-Fluoro-2-methoxyaniline 97%
25 g
$ 52.00

Matrix Scientific
4-Fluoro-2-methoxyaniline 95+%
5g
$ 47.00

Matrix Scientific
4-Fluoro-2-methoxyaniline 95+%
1g
$ 17.00

Crysdot
4-Fluoro-2-methoxyaniline 98%
25g
$ 79.00

Chemenu
4-Fluoro-2-methoxyaniline 95%
100g
$ 473.00

American Custom Chemicals Corporation
4-FLUORO-2-METHOXYANILINE 95.00%
5G
$ 1421.65

Total 90 raw suppliers

Chemical Property of 4-Fluoro-2-methoxyaniline

Chemical Property:

Vapor Pressure:0.22mmHg at 25°C
Refractive Index:1.532
Boiling Point:207.891 °C at 760 mmHg
PKA:4.60±0.10(Predicted)
Flash Point:79.53 °C
PSA：35.25000
Density:1.177 g/cm³
LogP:1.99770
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:141.058992041
Heavy Atom Count:10
Complexity:110

Purity/Quality:

99%, ^*data from raw suppliers

4-?Fluoro-?2-?methoxyaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)F)N

Technology Process of 4-Fluoro-2-methoxyaniline

There total 8 articles about 4-Fluoro-2-methoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 448-19-1
4-fluoro-2-methoxy-1-nitrobenzene

: 450-91-9
4-fluoro-2-methoxyaniline

Guidance literature:: With hydrogen; 5%-palladium/activated carbon; In ethanol; for 1h; under 1551.49 Torr;

Reference yield: 13.0%

: 450-91-9
4-fluoro-2-methoxyaniline

Guidance literature:

Reference yield:

: 446-36-6
5-fluoro-2-nitrophenol

: 450-91-9
4-fluoro-2-methoxyaniline

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide / 15 h / 140 °C

2: H₂ / 10percent Pd/C / ethanol / 16 h / 760 Torr

With hydrogen; potassium carbonate; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm970166j