1-benzyl-2-tert-butyl-4-oxopyrazolidine-1,2-dicarboxylate

Base Information

Chemical Name:1-benzyl-2-tert-butyl-4-oxopyrazolidine-1,2-dicarboxylate
CAS No.:503072-63-7
Molecular Formula:C16H20N2O5
Molecular Weight:320.345
Hs Code.:
Mol file:503072-63-7.mol

Synonyms:Jervaic acid;;Jervasic acid;;4-OXO-4H-PYRAN-2,6-DICARBOXYLIC ACID;;4-oxo-pyran-2,6-dicarboxylate;;4-oxo-pyrazolidine-1,2-dicarboxylic acid 1-benzyl ester 2-tert-butyl ester;;chelidonic acid;;

Suppliers and Price of 1-benzyl-2-tert-butyl-4-oxopyrazolidine-1,2-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-Benzyl2-tert-butyl4-oxopyrazolidine-1,2-dicarboxylate 95+%
1g
$ 374.00

Total 9 raw suppliers

Chemical Property of 1-benzyl-2-tert-butyl-4-oxopyrazolidine-1,2-dicarboxylate

Chemical Property:

Boiling Point:431.2±55.0 °C(Predicted)
PKA:-2.39±0.20(Predicted)
PSA：76.15000
Density:1.266±0.06 g/cm3 (20 oC 760 Torr), Calc.*
LogP:2.23580

Purity/Quality:

97% ^*data from raw suppliers

1-Benzyl2-tert-butyl4-oxopyrazolidine-1,2-dicarboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-benzyl-2-tert-butyl-4-oxopyrazolidine-1,2-dicarboxylate

There total 2 articles about 1-benzyl-2-tert-butyl-4-oxopyrazolidine-1,2-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 503072-28-4
4-methylenepyrazolidine-1,2-dicarboxylic acid 1-benzyl ester 2-tert-butyl ester

: 503072-63-7
4-oxo-pyrazolidine-1,2-dicarboxylic acid 1-benzyl ester 2-tert-butyl ester

Guidance literature:: 4-methylenepyrazolidine-1,2-dicarboxylic acid 1-benzyl ester 2-tert-butyl ester; With ozone; In dichloromethane;

With dimethylsulfide; In dichloromethane;
DOI:10.1016/j.bmcl.2004.06.001

Reference yield:

: 5331-43-1
N-benzyloxycarbonyl-hydrazine

: 503072-63-7
4-oxo-pyrazolidine-1,2-dicarboxylic acid 1-benzyl ester 2-tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: 99 percent / Et₃N / CH₂Cl₂

2.1: 96 percent / NaH / dimethylformamide

3.1: O₃ / CH₂Cl₂

3.2: 56 percent / dimethylsulfane / CH₂Cl₂

With sodium hydride; ozone; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2004.06.001