Ethyl 2-(2-benzhydrylidenehydrazinyl)-2-oxoacetate

Base Information

• Chemical Name: Ethyl 2-(2-benzhydrylidenehydrazinyl)-2-oxoacetate
• CAS No.: 106532-14-3
• Molecular Formula: C₁₇H₁₆N₂O₃
• Molecular Weight: 296.326
• DSSTox Substance ID: DTXSID80365447
• ChEMBL ID: CHEMBL1719044
• Mol file: 106532-14-3.mol

Synonyms:ethyl 2-(2-benzhydrylidenehydrazinyl)-2-oxoacetate;MLS001029661;CHEMBL1719044;DTXSID80365447;HMS2776L13;STL329622;AKOS022107336;SMR000427023;ethyl [2-(diphenylmethylidene)hydrazinyl](oxo)acetate;(N'-Benzhydrylidene-hydrazino)-oxo-acetic acid ethyl ester;106532-14-3

Chemical Property of Ethyl 2-(2-benzhydrylidenehydrazinyl)-2-oxoacetate

Chemical Property:

• Density: 1.14g/cm³
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 296.11609238
• Heavy Atom Count: 22
• Complexity: 388

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C(=O)NN=C(C1=CC=CC=C1)C2=CC=CC=C2

Technology Process of Ethyl 2-(2-benzhydrylidenehydrazinyl)-2-oxoacetate

There total 1 articles about Ethyl 2-(2-benzhydrylidenehydrazinyl)-2-oxoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzophenone (119-61-9) + oxalic acid diethyl ester (95-92-1) → benzhydrylidenehydrazide of ethyl hydrogen oxalate (106532-14-3)

Guidance literature:

With hydrogenchloride; hydrazine hydrate; Yield given. Multistep reaction; 1.) ethanol, 15 deg C; 2.) 2-propanol, 1 day;

Reference yield: 65.0%

phenylmagnesium bromide + benzhydrylidenehydrazide of ethyl hydrogen oxalate (106532-14-3) → benzhydrylidenehydrazide of benzilic acid (106532-15-4)

Guidance literature:

In diethyl ether; for 1h;

Reference yield: 64.0%

(4-chlorphenyl)magnesium bromide (873-77-8) + benzhydrylidenehydrazide of ethyl hydrogen oxalate (106532-14-3) → Bis-(4-chloro-phenyl)-hydroxy-acetic acid benzhydrylidene-hydrazide

Guidance literature:

In diethyl ether; for 1h;

upstream raw materials:

benzophenone

oxalic acid diethyl ester

Downstream raw materials:

benzhydrylidenehydrazide of benzilic acid