3-Phenylazetidine Hydrochloride

Base Information

• Chemical Name: 3-Phenylazetidine Hydrochloride
• CAS No.: 7606-30-6
• Molecular Formula: C9H12ClN
• Molecular Weight: 169.654
• Hs Code.: 2933998090
• Mol file: 7606-30-6.mol

Synonyms:3-PHENYL-AZETIDINE HYDROCHLORIDE;3-PHENYLAZETIDINE HCL;

Chemical Property of 3-Phenylazetidine Hydrochloride

Chemical Property:

• PSA: 12.03000
• LogP: 2.50420
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

3-PhenylazetidineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-Phenylazetidine Hydrochloride is the acidic form of 3-Phenylazetidine (P319525), which is a substituted azetidine which shows analgesics and sympathomimetics effects.

Technology Process of 3-Phenylazetidine Hydrochloride

There total 1 articles about 3-Phenylazetidine Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

tert-butyl 3-phenylazetidine-1-carboxylate → 3-phenylazetidine hydrochloride (7606-30-6)

Guidance literature:

With hydrogenchloride; In methanol; water; at 25 ℃; for 6h;

Reference yield: 99.0%

3-phenylazetidine hydrochloride (7606-30-6) + 5-(5-chloropyridin-2-yl)isoxazole-3-carboxylic acid → (5-(5-chloropyridin-2-yl)isoxazol-3-yl)(3-phenylazetidin-1-yl)methanone

Guidance literature:

With triethylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

Reference yield: 40.0%

4,5,6,7-tetrahydrobenzo[d]isoxazole-3-carboxylic acid (90005-77-9) + 3-phenylazetidine hydrochloride (7606-30-6) → 3-(3-phenylazetidine-1-carbonyl)-4,5,6,7-tetrahydro-1,2-benzoxazole

Guidance literature:

With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 25 ℃; for 16h;

Downstream raw materials:

3-phenyl-6-(3-phenylazetidin-1-ylmethyl)-7H-imidazo-[1,5-a]pyrazin-8-one

Refernces