6-Amino-2,3-dichlorobenzoic acid

Base Information

• Chemical Name: 6-Amino-2,3-dichlorobenzoic acid
• CAS No.: 20776-60-7
• Molecular Formula: C7H5Cl2NO2
• Molecular Weight: 206.028
• Hs Code.: 2922499990
• DSSTox Substance ID: DTXSID90477646
• Nikkaji Number: J83.024K
• Mol file: 20776-60-7.mol

Synonyms:6-Amino-2,3-dichlorobenzoic acid;20776-60-7;2-AMINO-5,6-DICHLOROBENZOIC ACID;Benzoic acid, 6-amino-2,3-dichloro-;Dopexaminehydrochloride;5,6-dichloroanthranilic acid;SCHEMBL7015064;6-Amino-2,3-dichlorobenzoicacid;DTXSID90477646;SRTBBLNAKMLZTN-UHFFFAOYSA-N;6-amino-2, 3-dichlorobenzoic acid;AKOS015960245;AB15584;AC-10029;CS-0333650;FT-0611141;2-amino-5,6-dichlorobenzoic acid, AldrichCPR;C90815;A929567

Chemical Property of 6-Amino-2,3-dichlorobenzoic acid

Chemical Property:

• Vapor Pressure: 4.21E-06mmHg at 25°C
• Melting Point: 176-177 °C (decomp)
• Refractive Index: 1.658
• Boiling Point: 369.2°C at 760 mmHg
• PKA: 0.53±0.25(Predicted)
• Flash Point: 177.1°C
• PSA: 63.32000
• Density: 1.607g/cm³
• LogP: 2.85500
• Storage Temp.: 2-8°C
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 204.9697338
• Heavy Atom Count: 12
• Complexity: 188

Purity/Quality:

98%min ^*data from raw suppliers

6-Amino-2,3-dichlorobenzoicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C(=C1N)C(=O)O)Cl)Cl

Technology Process of 6-Amino-2,3-dichlorobenzoic acid

There total 8 articles about 6-Amino-2,3-dichlorobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4,5-Dichloro-1H-indole-2,3-dione (1677-47-0) → 6-amino-2,3-dichlorobenzoic acid (20776-60-7)

Guidance literature:

Reference yield:

2,3-dichloro-6-nitrobenzoic acid (13300-62-4) → 6-amino-2,3-dichlorobenzoic acid (20776-60-7)

Guidance literature:

In methanol; palladium-carbon;

Reference yield:

2,3-Dichloro-6-p-tolylazo-benzoic acid → 6-amino-2,3-dichlorobenzoic acid (20776-60-7)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol;

DOI:10.1246/bcsj.41.424

upstream raw materials:

4,5-Dichloro-1H-indole-2,3-dione

N-(α-Oximino-acetyl)-3.4-dichlor-anilin

4-chloroisatin

2,3-dichloro-6-nitrobenzoic acid

Downstream raw materials:

6-(carboxymethyl-amino)-2,3-dichloro-benzoic acid

anagrelide

anagrelide hydrochloride

m,p-dichloroaniline