1,3-Dimethyl-6-cyanouracil

Base Information

• Chemical Name: 1,3-Dimethyl-6-cyanouracil
• CAS No.: 49846-86-8
• Molecular Formula: C7H7N3O2
• Molecular Weight: 165.151
• Hs Code.: 2933599090
• Mol file: 49846-86-8.mol

Synonyms:1,3-DIMETHYL-6-CYANOURACIL;1,3-diMethyl-2,6-dioxo-1,2,3,6-tetrahydropyriMidine-4-carbonitrile

Chemical Property of 1,3-Dimethyl-6-cyanouracil

Chemical Property:

• Vapor Pressure: 0.0219mmHg at 25°C
• Melting Point: 160-163 °C
• Refractive Index: 1.579
• Boiling Point: 250.2 °C at 760 mmHg
• PKA: -3.85±0.40(Predicted)
• Flash Point: 105.1 °C
• PSA: 67.79000
• Density: 1.37 g/cm³
• LogP: -1.04432

Purity/Quality:

98%min ^*data from raw suppliers

1,3-DIMETHYL-6-CYANOURACIL 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-Dimethyl-6-cyanouracil

There total 1 articles about 1,3-Dimethyl-6-cyanouracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4,7-Trimethyl-3,5-dioxo-8-phenyl-2,4-diaza-bicyclo[4.2.0]oct-7-ene-1-carbonitrile (74226-45-2) → 1-Phenylprop-1-yne (673-32-5) + 6-cyano-1,3-dimethyluracil (49846-86-8) + (4aS,10bS)-1,3,5-Trimethyl-2,4-dioxo-1,2,3,4,4a,10b-hexahydro-benzo[h]quinazoline-6-carbonitrile (75326-41-9)

Guidance literature:

Irradiation; 254nm;

DOI:10.1016/S0040-4039(00)92595-4

Reference yield: 90.0%

6-cyano-1,3-dimethyluracil (49846-86-8) + ethylmagnesium bromide (925-90-6) → 1,3-dimethyl-6-ethyluracil (49786-02-9)

Guidance literature:

With zinc(II) chloride; In tetrahydrofuran; diethyl ether; at 0 - 20 ℃; for 3h; Temperature; Time; Solvent; Concentration; Reagent/catalyst;

DOI:10.1021/jo400364p

Reference yield: 87.0%

6-cyano-1,3-dimethyluracil (49846-86-8) + 4-but-1-enylmagnesium bromide (7103-09-5) → C10H14N2O2 (1429644-25-6)

Guidance literature:

With zinc(II) chloride; In tetrahydrofuran; diethyl ether; at 0 - 20 ℃; for 3h;

DOI:10.1021/jo400364p

upstream raw materials:

2,4,7-Trimethyl-3,5-dioxo-8-phenyl-2,4-diaza-bicyclo[4.2.0]oct-7-ene-1-carbonitrile

Downstream raw materials:

2,4,7-Trimethyl-3,5-dioxo-8-phenyl-2,4-diaza-bicyclo[4.2.0]oct-7-ene-1-carbonitrile

(4aS,10bS)-1,3,5-Trimethyl-2,4-dioxo-1,2,3,4,4a,10b-hexahydro-benzo[h]quinazoline-6-carbonitrile

(E)-3-(1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-2-phenyl-but-2-enenitrile

(Z)-3-(1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-2-phenyl-but-2-enenitrile