Pyrrolidine-1-sulfonamide

Base Information

• Chemical Name: Pyrrolidine-1-sulfonamide
• CAS No.: 4108-88-7
• Molecular Formula: C4H10N2O2S
• Molecular Weight: 150.202
• Hs Code.: 2935009090
• European Community (EC) Number: 839-433-2
• DSSTox Substance ID: DTXSID90577110
• Nikkaji Number: J2.823.186E
• Wikidata: Q82467034
• Mol file: 4108-88-7.mol

Synonyms:pyrrolidine-1-sulfonamide;4108-88-7;1-Pyrrolidinesulfonamide;MFCD11171672;1-Pyrrolidinesulfoamide;pyrrolidine-1-sulfonic acid amide;pyrrolidine sulfonamide;1-Pyrrolidinesulfonamide(7CI,8CI,9CI);SCHEMBL391423;DTXSID90577110;LPPOVVJDAVMOET-UHFFFAOYSA-N;AMY16288;AKOS009161477;BS-13066;SY178090;CS-0060805;EN300-41339;F12022;AB01002789-01;A825426;Z300098708

Chemical Property of Pyrrolidine-1-sulfonamide

Chemical Property:

• Boiling Point: 287.488 °C at 760 mmHg
• Flash Point: 127.668 °C
• PSA: 71.78000
• Density: 1.408 g/cm³
• LogP: 1.00470
• Storage Temp.: 2-8°C
• XLogP3: -0.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 150.04629874
• Heavy Atom Count: 9
• Complexity: 175

Purity/Quality:

97% ^*data from raw suppliers

Pyrrolidine-1-sulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(C1)S(=O)(=O)N

Technology Process of Pyrrolidine-1-sulfonamide

There total 4 articles about Pyrrolidine-1-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ (2S)-1-pyrrolidinesulfonamide (4108-88-7)

Guidance literature:

With palladium on activated charcoal; hydrogen; In methanol; for 3h;

Reference yield: 85.0%

pyrrolidine (123-75-1) → (2S)-1-pyrrolidinesulfonamide (4108-88-7)

Guidance literature:

With SULFAMIDE; In 1,4-dioxane; for 24h; Reflux;

DOI:10.3390/molecules26061611

Reference yield:

pyrrolidine (123-75-1) + 4-nitrophenyl sulfamate (108555-00-6) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + (2S)-1-pyrrolidinesulfonamide (4108-88-7)

Guidance literature:

In acetonitrile; at 36.85 ℃; Further Variations:; Reaction partners; Kinetics;

DOI:10.1002/poc.1050

upstream raw materials:

pyrrolidine

4-nitrophenyl sulfamate

[N-(tert-butoxycarbonyl)]-pyrrolidine-1-sulfonic acid amide

Downstream raw materials:

C₂₇H₃₀N₄O₄S

C₃₃H₄₀N₄O₅S

C₃₃H₃₈N₄O₅S

2-fluoro-N-(pyrrolidin-1-ylsulfonyl)benzamide