[14-(2-Bromo-allyloxy)-tetradec-1-ynyl]-methyl-phenyl-amine

Base Information

• Chemical Name: [14-(2-Bromo-allyloxy)-tetradec-1-ynyl]-methyl-phenyl-amine
• CAS No.: 75416-58-9
• Molecular Formula: C₂₄H₃₆BrNO
• Molecular Weight: 434.46
• Mol file: 75416-58-9.mol

Synonyms:

Chemical Property of [14-(2-Bromo-allyloxy)-tetradec-1-ynyl]-methyl-phenyl-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [14-(2-Bromo-allyloxy)-tetradec-1-ynyl]-methyl-phenyl-amine

There total 6 articles about [14-(2-Bromo-allyloxy)-tetradec-1-ynyl]-methyl-phenyl-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclododecanone (830-13-7) → [14-(2-Bromo-allyloxy)-tetradec-1-ynyl]-methyl-phenyl-amine (75416-58-9)

Guidance literature:

Multi-step reaction with 6 steps

1: 90 percent / MCPBA / CH₂Cl₂ / 20 h / Heating

2: 97 percent / HCl / 3 h / 25 °C

3: 85 percent / diisopropylethylamine / 18 h / 150 °C / other reaction conditions

4: 1.) LiAlH₄, 2.) H₂O / 1.)Et₂O, 2 h

5: methyltriphenoxyphosphonium iodide

6: 2.) NH₄Cl/NH₄OH / 1.) HMPA, THF, 70 deg C, 3 h, 2.) -40 deg C

With hydrogenchloride; ammonium hydroxide; lithium aluminium tetrahydride; methyltriphenoxyphosphonium iodide; water; ammonium chloride; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;

DOI:10.1016/S0040-4039(00)92763-1

Reference yield:

oxacyclotridecan-2-one (947-05-7) → [14-(2-Bromo-allyloxy)-tetradec-1-ynyl]-methyl-phenyl-amine (75416-58-9)

Guidance literature:

Multi-step reaction with 5 steps

1: 97 percent / HCl / 3 h / 25 °C

2: 85 percent / diisopropylethylamine / 18 h / 150 °C / other reaction conditions

3: 1.) LiAlH₄, 2.) H₂O / 1.)Et₂O, 2 h

4: methyltriphenoxyphosphonium iodide

5: 2.) NH₄Cl/NH₄OH / 1.) HMPA, THF, 70 deg C, 3 h, 2.) -40 deg C

With hydrogenchloride; ammonium hydroxide; lithium aluminium tetrahydride; methyltriphenoxyphosphonium iodide; water; ammonium chloride; N-ethyl-N,N-diisopropylamine;

DOI:10.1016/S0040-4039(00)92763-1

Reference yield:

methyl 12-hydroxydodecanoate (71655-36-2) → [14-(2-Bromo-allyloxy)-tetradec-1-ynyl]-methyl-phenyl-amine (75416-58-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 85 percent / diisopropylethylamine / 18 h / 150 °C / other reaction conditions

2: 1.) LiAlH₄, 2.) H₂O / 1.)Et₂O, 2 h

3: methyltriphenoxyphosphonium iodide

4: 2.) NH₄Cl/NH₄OH / 1.) HMPA, THF, 70 deg C, 3 h, 2.) -40 deg C

With ammonium hydroxide; lithium aluminium tetrahydride; methyltriphenoxyphosphonium iodide; water; ammonium chloride; N-ethyl-N,N-diisopropylamine;

DOI:10.1016/S0040-4039(00)92763-1

upstream raw materials:

Lithium

1-(2-Bromo-allyloxy)-12-iodo-dodecane

oxacyclotridecan-2-one

methyl 12-hydroxydodecanoate

Downstream raw materials:

14-(Methyl-phenyl-amino)-tetradec-13-yn-1-ol

Methyl-((Z)-oxacyclopentadec-2-en-2-yl)-phenyl-amine