C₂₀H₂₇NO₃

Base Information

• Chemical Name: C₂₀H₂₇NO₃
• CAS No.: 1430812-93-3
• Molecular Formula: C₂₀H₂₇NO₃
• Molecular Weight: 329.439
• Mol file: 1430812-93-3.mol

Synonyms:

Chemical Property of C₂₀H₂₇NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₇NO₃

There total 1 articles about C₂₀H₂₇NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dec-9-enoic acid (14436-32-9) + (R)-4-(phenylmethyl)-2-oxazolidinone (40217-17-2,90719-32-7,120574-96-1,102029-44-7) → C20H27NO3 (1430812-93-3)

Guidance literature:

dec-9-enoic acid; With pivaloyl chloride; triethylamine; lithium chloride; at -20 ℃;

(R)-4-(phenylmethyl)-2-oxazolidinone; With n-butyllithium; In tetrahydrofuran; at -78 ℃;

DOI:10.1016/j.tetlet.2013.03.006

Reference yield:

C20H27NO3 (1430812-93-3) + methyl iodide (74-88-4) → C21H29NO3

Guidance literature:

With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃;

DOI:10.1016/j.tetlet.2013.03.006

Reference yield:

C20H27NO3 (1430812-93-3) → C53H69NO9

Guidance literature:

Multi-step reaction with 4 steps

1: sodium hexamethyldisilazane / tetrahydrofuran / -78 °C

2: lithium hydroxide; dihydrogen peroxide / tetrahydrofuran; water / 0 °C

3: dicyclohexyl-carbodiimide; dmap / dichloromethane

4: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / Reflux

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; dmap; dihydrogen peroxide; sodium hexamethyldisilazane; dicyclohexyl-carbodiimide; lithium hydroxide; In tetrahydrofuran; dichloromethane; water;

DOI:10.1016/j.tetlet.2013.03.006

upstream raw materials:

dec-9-enoic acid

(R)-4-(phenylmethyl)-2-oxazolidinone