Technology Process of AF-toxin IIc
There total 17 articles about AF-toxin IIc which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: sodium nitrite
2: p-toluenesulphonic acid
3: lithium carbonate, water / methanol
4: imidazole / dimethylformamide
5: H2 / palladium on carbon / ethanol
6: dicyclohexylcarbodiimide, 4-pyrrolidinopyridine / CH2Cl2
7: sodium hydride / aq. ethanol / Ambient temperature
8: tetrabutylammonium fluoride
With
1H-imidazole; tetrabutyl ammonium fluoride; water; hydrogen; lithium carbonate; sodium hydride; 4-pyrrolidin-1-ylpyridine; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; sodium nitrite;
palladium on activated charcoal;
In
methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.34.2668
- Guidance literature:
-
Multi-step reaction with 7 steps
1: p-toluenesulphonic acid
2: lithium carbonate, water / methanol
3: imidazole / dimethylformamide
4: H2 / palladium on carbon / ethanol
5: dicyclohexylcarbodiimide, 4-pyrrolidinopyridine / CH2Cl2
6: sodium hydride / aq. ethanol / Ambient temperature
7: tetrabutylammonium fluoride
With
1H-imidazole; tetrabutyl ammonium fluoride; water; hydrogen; lithium carbonate; sodium hydride; 4-pyrrolidin-1-ylpyridine; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide;
palladium on activated charcoal;
In
methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.34.2668
- Guidance literature:
-
Multi-step reaction with 6 steps
1: lithium carbonate, water / methanol
2: imidazole / dimethylformamide
3: H2 / palladium on carbon / ethanol
4: dicyclohexylcarbodiimide, 4-pyrrolidinopyridine / CH2Cl2
5: sodium hydride / aq. ethanol / Ambient temperature
6: tetrabutylammonium fluoride
With
1H-imidazole; tetrabutyl ammonium fluoride; water; hydrogen; lithium carbonate; sodium hydride; 4-pyrrolidin-1-ylpyridine; dicyclohexyl-carbodiimide;
palladium on activated charcoal;
In
methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.34.2668
