C₃₂H₅₁N₅O₆

Base Information

• Chemical Name: C₃₂H₅₁N₅O₆
• CAS No.: 1609169-86-9
• Molecular Formula: C₃₂H₅₁N₅O₆
• Molecular Weight: 601.787
• Mol file: 1609169-86-9.mol

Synonyms:

Chemical Property of C₃₂H₅₁N₅O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₂H₅₁N₅O₆

There total 11 articles about C₃₂H₅₁N₅O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C32H53N5O7 → C32H51N5O6 (1609169-86-9)

Guidance literature:

With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; O-(benzotriazol-1-yl)-N,N,N,N-tetramethyluroniumhexafluorophosphate; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;

DOI:10.1039/c3md00294b

Reference yield:

L-tyrosine (60-18-4,18875-48-4,25619-78-7,30704-25-7) → C32H51N5O6 (1609169-86-9)

Guidance literature:

Multi-step reaction with 7 steps

1: thionyl chloride

2: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 20 °C

3: trifluoroacetic acid / dichloromethane / 20 °C

4: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 20 °C

5: lithium hydroxide / tetrahydrofuran / 20 °C

6: trifluoroacetic acid / dichloromethane / 20 °C

7: N-ethyl-N,N-diisopropylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; O-(benzotriazol-1-yl)-N,N,N,N-tetramethyluroniumhexafluorophosphate / dichloromethane; N,N-dimethyl-formamide; tetrahydrofuran / 20 °C / Inert atmosphere

With thionyl chloride; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; O-(benzotriazol-1-yl)-N,N,N,N-tetramethyluroniumhexafluorophosphate; lithium hydroxide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1039/c3md00294b

Reference yield:

L-Tyr-OMe (1080-06-4) → C32H51N5O6 (1609169-86-9)

Guidance literature:

Multi-step reaction with 6 steps

1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 20 °C

2: trifluoroacetic acid / dichloromethane / 20 °C

3: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 20 °C

4: lithium hydroxide / tetrahydrofuran / 20 °C

5: trifluoroacetic acid / dichloromethane / 20 °C

6: N-ethyl-N,N-diisopropylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; O-(benzotriazol-1-yl)-N,N,N,N-tetramethyluroniumhexafluorophosphate / dichloromethane; N,N-dimethyl-formamide; tetrahydrofuran / 20 °C / Inert atmosphere

With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; O-(benzotriazol-1-yl)-N,N,N,N-tetramethyluroniumhexafluorophosphate; lithium hydroxide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1039/c3md00294b

upstream raw materials:

L-tyrosine

L-Tyr-OMe

N-tret-butoxycarbonyl-L-leucinyl-L-tyrosine methyl ester

N-Boc-D-Leu