Methyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate

Base Information

Chemical Name:Methyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate
CAS No.:52505-44-9
Molecular Formula:C₁₁H₁₂N₂O₂S
Molecular Weight:236.294
Hs Code.:
European Community (EC) Number:809-445-2
DSSTox Substance ID:DTXSID70967237
Wikidata:Q27210451
ChEMBL ID:CHEMBL1421830
Mol file:52505-44-9.mol

Synonyms:methyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate;52505-44-9;CHEMBL1421830;MFCD00453376;3-Amino-4,6-dimethyl-thieno[2,3-b]pyridine-2-carboxylic acid methyl ester;5278-19-3;MLS000711948;SCHEMBL19769197;DTXSID70967237;CHEBI:121855;HMS1675K20;HMS2643D23;CCA50544;BDBM50512257;STK788789;AKOS000275765;UPCMLD0ENAT5752253:001;11N-515S;SMR000281715;BB 0241030;CS-0117760;VU0012362-4;AB00078817-01;EN300-6509674;AG-205/03751006;SR-01000508691;SR-01000508691-1;Q27210451;Z51406231;F3253-0019;methyl3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate;3-amino-4,6-dimethyl-2-thieno[2,3-b]pyridinecarboxylic acid methyl ester;3-Amino-4,6-dimethyl-thieno[2,3-b]pyridine-2 -carboxylic acid methyl ester

Suppliers and Price of Methyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
METHYL-3-AMINO-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXYLATE 95.00%
5MG
$ 697.51

American Custom Chemicals Corporation
METHYL-3-AMINO-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXYLATE 95.00%
10MG
$ 692.49

American Custom Chemicals Corporation
METHYL-3-AMINO-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXYLATE 95.00%
1MG
$ 658.53

Total 3 raw suppliers

Chemical Property of Methyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:236.06194880
Heavy Atom Count:16
Complexity:287

Purity/Quality:

98%+ ^*data from raw suppliers

METHYL-3-AMINO-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=NC2=C1C(=C(S2)C(=O)OC)N)C

Technology Process of Methyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate

There total 4 articles about Methyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 14237-71-9
2-chloro-4,6-dimethylnicotinonitrile

: 2365-48-2
Methyl thioglycolate

: 52505-44-9
methyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate

Guidance literature:: With sodium ethanolate; In ethanol;
DOI:10.1007/BF00471900

Reference yield:

: 54585-47-6
4,6-Dimethyl-2-thioxo-1,2-dihydro-pyridine-3-carbonitrile

: 96-34-4
methyl chloroacetate

: 52505-44-9
methyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate

Guidance literature:: With sodium methylate; In methanol; at 20 ℃; for 3h;
DOI:10.1016/j.ejmech.2019.03.060

Reference yield:

: 123-54-6,81235-32-7
acetylacetone

: 52505-44-9
methyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 1,4-diaza-bicyclo[2.2.2]octane / ethanol / 6 h / Reflux

2: sodium methylate / methanol / 3 h / 20 °C

With 1,4-diaza-bicyclo[2.2.2]octane; sodium methylate; In methanol; ethanol;
DOI:10.1016/j.ejmech.2019.03.060