1-(2-Aminoethyl)piperidin-2-one

Base Information

Chemical Name:1-(2-Aminoethyl)piperidin-2-one
CAS No.:27578-61-6
Molecular Formula:C7H14N2O
Molecular Weight:142.201
Hs Code.:2933790090
DSSTox Substance ID:DTXSID80594432
Wikidata:Q72436908
Mol file:27578-61-6.mol

Synonyms:1-(2-Aminoethyl)piperidin-2-one;27578-61-6;1-(2-Amino-ethyl)-piperidin-2-one;2-Piperidinone, 1-(2-aminoethyl)-;1-(2-aminoethyl)-2-Piperidinone;SCHEMBL1446472;DTXSID80594432;CBA57861;AKOS000558724;SB36346;BS-22175;DB-003844;CS-0208384;1-(2-Aminoethyl)piperidin-2-one, AldrichCPR;EN300-58377;E79819

Suppliers and Price of 1-(2-Aminoethyl)piperidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
1-(2-Amino-ethyl)-piperidin-2-one 98%
1g
$ 198.00

J&W Pharmlab
1-(2-Amino-ethyl)-piperidin-2-one 98%
500mg
$ 149.00

J&W Pharmlab
1-(2-Amino-ethyl)-piperidin-2-one 98%
250mg
$ 125.00

J&W Pharmlab
1-(2-Amino-ethyl)-piperidin-2-one 98%
100mg
$ 108.00

J&W Pharmlab
1-(2-Amino-ethyl)-piperidin-2-one 98%
5g
$ 598.00

J&W Pharmlab
1-(2-Amino-ethyl)-piperidin-2-one 98%
25g
$ 1998.00

Chemenu
1-(2-Aminoethyl)piperidin-2-one 95%
5g
$ 707.00

American Custom Chemicals Corporation
1-(2-AMINOETHYL)-2-PIPERIDINONE 95.00%
5MG
$ 499.65

Alichem
1-(2-Aminoethyl)piperidin-2-one
1g
$ 199.92

Total 18 raw suppliers

Chemical Property of 1-(2-Aminoethyl)piperidin-2-one

Chemical Property:

Vapor Pressure:0.00251mmHg at 25°C
Boiling Point:287.2°C at 760 mmHg
PKA:9.01±0.10(Predicted)
Flash Point:127.5°C
PSA：46.33000
Density:1.051g/cm³
LogP:0.59580
XLogP3:-1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:142.110613074
Heavy Atom Count:10
Complexity:125

Purity/Quality:

98% ^*data from raw suppliers

1-(2-Amino-ethyl)-piperidin-2-one 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C(=O)C1)CCN

Technology Process of 1-(2-Aminoethyl)piperidin-2-one

There total 5 articles about 1-(2-Aminoethyl)piperidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-(2-(2-oxopiperidin-1-yl)ethyl)isoindoline-1,3-dione

: 27578-61-6
1-(2-aminoethyl)-2-piperidinone

Guidance literature:: With hydrazine hydrate; In methanol; at 0 - 20 ℃; for 12h;

Reference yield:

: 675-20-7
piperidin-2-one

: 27578-61-6
1-(2-aminoethyl)-2-piperidinone

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 - 5 °C / Inert atmosphere

1.2: 6 h / Reflux

2.1: hydrogenchloride / methanol / 0.5 h / 0 - 5 °C / Inert atmosphere

3.1: triphenylphosphine / tetrahydrofuran / 0.5 h / 0 - 5 °C / Inert atmosphere

3.2: 2 h / 0 - 20 °C

4.1: hydrazine hydrate / methanol / 12 h / 0 - 20 °C

With hydrogenchloride; hydrazine hydrate; sodium hydride; triphenylphosphine; In tetrahydrofuran; methanol; mineral oil;

Reference yield:

: 388630-64-6
1-(2-((tert-butyldimethylsilyl)oxy)ethyl)piperidin-2-one

: 27578-61-6
1-(2-aminoethyl)-2-piperidinone

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogenchloride / methanol / 0.5 h / 0 - 5 °C / Inert atmosphere

2.1: triphenylphosphine / tetrahydrofuran / 0.5 h / 0 - 5 °C / Inert atmosphere

2.2: 2 h / 0 - 20 °C

3.1: hydrazine hydrate / methanol / 12 h / 0 - 20 °C

With hydrogenchloride; hydrazine hydrate; triphenylphosphine; In tetrahydrofuran; methanol;