(R)-[(4-Methylphenyl)sulfinyl]acetic acid

Base Information

Chemical Name:(R)-[(4-Methylphenyl)sulfinyl]acetic acid
CAS No.:88981-65-1
Molecular Formula:C9H10O3S
Molecular Weight:198.243
Hs Code.:
Mol file:88981-65-1.mol

Synonyms:CH28635 (R)-(+)-P-TOLYLSULFINYLACETIC ACID;(R)-(+)-P-TOLYLSULFINYL ACETIC ACID;Acetic acid, [(4-methylphenyl)sulfinyl]-, (R)-;Acetic acid, [(R)-(4-methylphenyl)sulfinyl]-;

Suppliers and Price of (R)-[(4-Methylphenyl)sulfinyl]acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (R)-[(4-Methylphenyl)sulfinyl]acetic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:323.495°C at 760 mmHg
Flash Point:149.445°C
PSA：73.58000
Density:1.296g/cm³
LogP:2.05290

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (R)-[(4-Methylphenyl)sulfinyl]acetic acid

There total 6 articles about (R)-[(4-Methylphenyl)sulfinyl]acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 124-38-9,18923-20-1
carbon dioxide

: 1519-39-7
(R)-methyl p-tolyl sulfoxide

: 88981-65-1
(R_S)-p-tolylsulfinylacetic acid

Guidance literature:: (R)-methyl p-tolyl sulfoxide; With lithium diisopropyl amide;

carbon dioxide;

With water;
DOI:10.1016/j.tetlet.2010.01.012

Reference yield:

: 72298-24-9
(R)-(+)-ethyl-α-(para-tolylsulfinyl) acetate

: 88981-65-1
(R_S)-p-tolylsulfinylacetic acid

Guidance literature:: With sodium hydroxide; water; In ethanol; at 20 ℃; for 1h;
DOI:10.1021/ja056649r

Reference yield:

: 1519-39-7
(R)-methyl p-tolyl sulfoxide

: 88981-65-1
(R_S)-p-tolylsulfinylacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: (TMS)2NLi / tetrahydrofuran; hexane / 1 h / -78 °C

1.2: 72 percent / tetrahydrofuran; hexane / 1 h / 0 °C

2.1: 520 mg / NaOH; water / ethanol / 1 h / 20 °C

With sodium hydroxide; water; lithium hexamethyldisilazane; In tetrahydrofuran; ethanol; hexane;
DOI:10.1021/ja056649r