C₂₂H₂₄O₈

Base Information

• Chemical Name: C₂₂H₂₄O₈
• CAS No.: 252333-67-8
• Molecular Formula: C₂₂H₂₄O₈
• Molecular Weight: 416.428
• Mol file: 252333-67-8.mol

Synonyms:

Chemical Property of C₂₂H₂₄O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₄O₈

There total 5 articles about C₂₂H₂₄O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic anhydride (108-24-7) + (7’S,8R,8’R)-4,4’,7’-trihydroxy-3,3’-dimethoxylignano-9,9’-lactone (20268-71-7,347359-71-1) → C22H24O8 (252333-67-8)

Guidance literature:

With dmap; triethylamine; In ethyl acetate; at 60 ℃; for 3h; Inert atmosphere;

DOI:10.1002/adsc.201300392

Reference yield:

vanillin (121-33-5,8014-42-4) → C22H24O8 (252333-67-8)

Guidance literature:

Multi-step reaction with 5 steps

1: potassium carbonate / acetone / 4 h / Reflux; Inert atmosphere

2: zinc; ammonium chloride; (R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid / toluene; di-isopropyl ether / 16 h / 4 °C / Inert atmosphere

3: chloro(1,5-cyclooctadiene)rhodium(I) dimer; triethylamine / 1,4-dioxane; water / 2 h / 90 °C / Inert atmosphere

4: palladium on activated carbon; hydrogen / ethyl acetate / 16 h / 760.05 Torr / Inert atmosphere

5: triethylamine; dmap / ethyl acetate / 3 h / 60 °C / Inert atmosphere

With dmap; chloro(1,5-cyclooctadiene)rhodium(I) dimer; (R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid; palladium on activated carbon; hydrogen; potassium carbonate; ammonium chloride; triethylamine; zinc; In 1,4-dioxane; di-isopropyl ether; water; ethyl acetate; acetone; toluene;

DOI:10.1002/adsc.201300392

Reference yield:

3-methoxy-4-(phenylmethoxy)benzaldehyde (2426-87-1) → C22H24O8 (252333-67-8)

Guidance literature:

Multi-step reaction with 4 steps

1: zinc; ammonium chloride; (R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid / toluene; di-isopropyl ether / 16 h / 4 °C / Inert atmosphere

2: chloro(1,5-cyclooctadiene)rhodium(I) dimer; triethylamine / 1,4-dioxane; water / 2 h / 90 °C / Inert atmosphere

3: palladium on activated carbon; hydrogen / ethyl acetate / 16 h / 760.05 Torr / Inert atmosphere

4: triethylamine; dmap / ethyl acetate / 3 h / 60 °C / Inert atmosphere

With dmap; chloro(1,5-cyclooctadiene)rhodium(I) dimer; (R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid; palladium on activated carbon; hydrogen; ammonium chloride; triethylamine; zinc; In 1,4-dioxane; di-isopropyl ether; water; ethyl acetate; toluene;

DOI:10.1002/adsc.201300392

upstream raw materials:

acetic anhydride

(7’S,8R,8’R)-4,4’,7’-trihydroxy-3,3’-dimethoxylignano-9,9’-lactone

vanillin

3-methoxy-4-(phenylmethoxy)benzaldehyde

Refernces