4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde

Base Information

Chemical Name:4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde
CAS No.:958230-19-8
Molecular Formula:C8H5ClN2O
Molecular Weight:180.593
Hs Code.:2933990090
Mol file:958230-19-8.mol

Synonyms:1H-Pyrrolo[2,3-b]pyridine-5-carboxaldehyde, 4-chloro-;4-Chloro1H-pyrrolo[2,3-b]pyridine-5-carboxaldehyde;4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxaldehyde, 4-Chloro-5-formyl-1H-pyrrolo[2,3-b]pyridine;4-Chloro-7-azaindole-5-carboxaldehyde

Suppliers and Price of 4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde
500mg
$ 220.00

SynQuest Laboratories
4-Chloro-7-azaindole-5-carboxaldehyde
5 g
$ 750.00

SynQuest Laboratories
4-Chloro-7-azaindole-5-carboxaldehyde
1 g
$ 225.00

Sigma-Aldrich
4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde Aldrich
1g
$ 642.00

Matrix Scientific
4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde
500mg
$ 98.00

Matrix Scientific
4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde
100mg
$ 28.00

Crysdot
4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde 95+%
5g
$ 675.00

Crysdot
4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde 95+%
10g
$ 1125.00

Crysdot
4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde 95+%
1g
$ 225.00

Chemenu
4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde 95%+
1g
$ 165.00

Total 47 raw suppliers

Chemical Property of 4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde

Chemical Property:

Refractive Index:1.748
PKA:12.11±0.40(Predicted)
PSA：45.75000
Density:1.521 g/cm³
LogP:2.02880
Storage Temp.:2-8°C

Purity/Quality:

99% ^*data from raw suppliers

4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde

There total 3 articles about 4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 55052-28-3
4-chloro-7-azaindole

: 958230-19-8
4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0 - 20 °C

1.2: 20 °C

2.1: sec.-butyllithium / cyclohexane; tetrahydrofuran / 1.25 h / -78 °C

2.2: 1 h / -78 °C

With sec.-butyllithium; sodium hydride; In tetrahydrofuran; cyclohexane; mineral oil;

Reference yield:

: 55052-28-3
4-chloro-7-azaindole

: 958230-19-8
4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde

: 924655-39-0
4-chloro-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C

1.2: -78 - 20 °C

2.1: sec.-butyllithium / tetrahydrofuran; hexane / 0.75 h / -78 °C

2.2: 1 h / -78 °C

With n-butyllithium; sec.-butyllithium; In tetrahydrofuran; hexane;

Reference yield:

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 651744-48-8
4-chloro-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine

: 958230-19-8
4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde

: 924655-39-0
4-chloro-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde

Guidance literature:: 4-chloro-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine; With sec.-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.75h;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

With hydrogenchloride; sodium hydrogencarbonate; more than 3 stages;