2-Chloro-5-(trifluoromethyl)pyridine-3-boronic acid

Base Information

Chemical Name:2-Chloro-5-(trifluoromethyl)pyridine-3-boronic acid
CAS No.:536693-96-6
Molecular Formula:C6H4BClF3NO2
Molecular Weight:225.4
Hs Code.:2933399990
Mol file:536693-96-6.mol

Synonyms:2-chloro-5-(trifluoromethyl)pyridine-3-boronic acid;2-CHLORO-5-TRIFLUOROMETHYL-3-PYRIDINYL BORONIC ACID;2-CHLORO-5-TRIFLUOROMETHYLPYRIDIN-3-BORONIC ACID;2-chloro-5-(trifluoroMethyl)pyridin-3-yl-3-boronic acid;Boronic acid, [2-chloro-5-(trifluoroMethyl)-3-pyridinyl]- (9CI);[2-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-3-YL]BORONIC ACID

Suppliers and Price of 2-Chloro-5-(trifluoromethyl)pyridine-3-boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-5-(trifluoromethyl)pyridine-3-boronicacid
100mg
$ 45.00

Crysdot
2-Chloro-5-(trifluoromethyl)pyridine-3-boronicacid 95+%
5g
$ 342.00

Crysdot
2-Chloro-5-(trifluoromethyl)pyridine-3-boronicacid 95+%
10g
$ 570.00

Chemenu
2-chloro-5-(trifluoromethyl)pyridin-3-yl-3-boronicacid 0.95
1g
$ 130.00

Biosynth Carbosynth
2-Chloro-5-(Trifluoromethyl)Pyridine-3-Boronic Acid
1 g
$ 250.00

Biosynth Carbosynth
2-Chloro-5-(Trifluoromethyl)Pyridine-3-Boronic Acid
500 mg
$ 160.00

Biosynth Carbosynth
2-Chloro-5-(Trifluoromethyl)Pyridine-3-Boronic Acid
250 mg
$ 100.00

Biosynth Carbosynth
2-Chloro-5-(Trifluoromethyl)Pyridine-3-Boronic Acid
100 mg
$ 55.00

Biosynth Carbosynth
2-Chloro-5-(Trifluoromethyl)Pyridine-3-Boronic Acid
2 g
$ 360.00

American Custom Chemicals Corporation
2-CHLORO-5-(TRIFLUOROMETHYL)PYRIDINE-3-BORONIC ACID 95.00%
1G
$ 253.05

Total 28 raw suppliers

Chemical Property of 2-Chloro-5-(trifluoromethyl)pyridine-3-boronic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:336.421ºC at 760 mmHg
Flash Point:157.262ºC
PSA：53.35000
Density:1.572g/cm3
LogP:0.43360
Storage Temp.:2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Chloro-5-(trifluoromethyl)pyridine-3-boronicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Chloro-5-(trifluoromethyl)pyridine-3-boronic acid

There total 3 articles about 2-Chloro-5-(trifluoromethyl)pyridine-3-boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 52334-81-3
2-chloro-5-trifluoromethylpyridine

: 536693-96-6
2-chloro-5-(trifluoromethyl)-3-pyridylboronic acid

: 1167437-28-6
2-chloro-5-(trifluoromethyl)-4-pyridylboronic acid

Guidance literature:: 2-chloro-5-trifluoromethylpyridine; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 ℃; for 2.25h; Inert atmosphere;

With Triisopropyl borate; In tetrahydrofuran; hexane; at -78 ℃; Inert atmosphere;

With water; In tetrahydrofuran; hexane; at -10 ℃;
DOI:10.1039/b901024f

Reference yield: 25.0%

: 5419-55-6
Triisopropyl borate

: 52334-81-3
2-chloro-5-trifluoromethylpyridine

: 536693-96-6
2-chloro-5-(trifluoromethyl)-3-pyridylboronic acid

: 1167437-28-6
2-chloro-5-(trifluoromethyl)-4-pyridylboronic acid

Guidance literature:: With CH₃CH₂CH₂CH₂Li; HN(CH(CH₃)2)2; In tetrahydrofuran; treatment of pyridine deriv. with butyllithium and amine deriv. in THF at -78°C for 2 h, treatment with borate deriv. at -78°C for0.5 h, treatment with water and acetic acid at room temp.; chromy., NMR;
DOI:10.1039/b901024f