1,2-adduct from 7

Base Information

• Chemical Name: 1,2-adduct from 7
• CAS No.: 55830-02-9
• Molecular Formula: C₁₄H₂₀O
• Molecular Weight: 204.312
• Mol file: 55830-02-9.mol

Synonyms:

Chemical Property of 1,2-adduct from 7

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-adduct from 7

There total 5 articles about 1,2-adduct from 7 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

Bis(tetramethylethylendiamin)lithium tetrakis-t-butyllutetat(III) + (E)-benzalacetone (1896-62-4) → 1,2-adduct from 7 (55830-02-9) + 1,4-adduct from 7 (63096-65-1)

Guidance literature:

In tetrahydrofuran; at 66 ℃; for 1h;

DOI:10.1016/S0022-328X(00)99709-2

Reference yield:

(E)-benzylidenepinacolone (538-44-3,28435-47-4,29569-91-3) + methyllithium (917-54-4) → 1,2-adduct from 7 (55830-02-9)

Guidance literature:

In diethyl ether;

DOI:10.1021/ja00843a027

Reference yield:

tert-butylmagnesium chloride (677-22-5) + (E)-benzalacetone (1896-62-4) → 1,2-adduct from 7 (55830-02-9) + 1,4-adduct from 7 (63096-65-1)

Guidance literature:

In tetrahydrofuran; at 0 - 20 ℃; for 16h;

DOI:10.1016/S0040-4039(01)02263-8

upstream raw materials:

(E)-benzylidenepinacolone

methyllithium

methylmagnesium bromide

tert-butylmagnesium bromide